Recombinant Human MYC Protein, MYC/DDK-tagged, C13 and N15-labeled

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Recombinant Human MYC Protein, MYC/DDK-tagged, C13 and N15-labeled

MYC Related Products

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Cat.No. : MYC-060H
Product Overview : MYC MS Standard C13 and N15-labeled recombinant protein (NP_002458) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 50.5 kDa
AA Sequence : Tags(s)LDF FRVVENQQPP ATMPLNVSFT NRNYDLDYDS VQPYFYCDEE ENFYQQQQQS ELQPPAPSED IWKKFELLPT PPLSPSRRSG LCSPSYVAVT PFSLRGDNDG GGGSFSTADQ LEMVTELLGG DMVNQSFICD PDDETFIKNI IIQDCMWSGF SAAAKLVSEK LASYQAARKD SGSPNPARGH SVCSTSSLYL QDLSAAASEC IDPSVVFPYP LNDSSSPKSC ASQDSSAFSP SSDSLLSSTE SSPQGSPEPL VLHEETPPTT SSDSEEEQED EEEIDVVSVE KRQAPGKRSE SGSPSAGGHS KPPHSPLVLK RCHVSTHQHN YAAPPSTRKD YPAAKRVKLD SVRVLRQISN NRKCTSPRSS DTEENVKRRT HNVLERQRRN ELKRSFFALR DQIPELENNE KAPKVVILKK ATAYILSVQA EEQKLISEED LLRKRREQLK HKLEQLRNSC ATRTRPLEQK LISEEDLAAN DILDYKDDDD KV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : MYC MYC proto-oncogene, bHLH transcription factor [ Homo sapiens (human) ]
Official Symbol : MYC
Synonyms : MYC; MYC proto-oncogene, bHLH transcription factor; bHLHe39; c-Myc; MRTL; MYCC; myc proto-oncogene protein; avian myelocytomatosis viral oncogene homolog; class E basic helix-loop-helix protein 39; myc-related translation/localization regulatory factor; proto-oncogene c-Myc; transcription factor p64; v-myc avian myelocytomatosis viral oncogene homolog; v-myc myelocytomatosis viral oncogene homolog;
Gene ID : 4609
mRNA Refseq : NM_002467
Protein Refseq : NP_002458
MIM : 190080
UniProt ID : P01106
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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