| Description : |
This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants encoding different isoforms have been characterized. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
100 kDa |
| AA Sequence : |
MNAPERQPQPDGGDAPGHEPGGSPQ DELDFSILFDYEYLNPNEEEPNAHK VASPPSGPAYPDDVLDYGLKPYSPL ASLSGEPPGRFGEPDRVGPQKFLSA AKPAGASGLSPRIEITPSHELIQAV GPLRMRDAGLLVEQPPLAGVAASPR FTLPVPGFEGYREPLCLSPASSGSS ASFISDTFSPYTSPCVSPNNGGPDD LCPQFQNIPAHYSPRTSPIMSPRTS LAEDSCLGRHSPVPRPASRSSSPGA KRRHSCAEALVALPPGASPQRSRSP SPQPSSHVAPQDHGSPAGYPPVAGS AVIMDALNSLATDSPCGIPPKMWKT SPDPSPVSAAPSKAGLPRHIYPAVE FLGPCEQGERRNSAPESILLVPPTW PKPLVPAIPICSIPVTASLPPLEWP LSSQSGSYELRIEVQPKPHHRAHYE TEGSRGAVKAPTGGHPVVQLHGYME NKPLGLQIFIGTADERILKPHAFYQ VHRITGKTVTTTSYEKIVGNTKVLE IPLEPKNNMRATIDCAGILKLRNAD IELRKGETDIGRKNTRVRLVFRVHI PESSGRIVSLQTASNPIECSQRSAH ELPMVERQDTDSCLVYGGQQMILTG QNFTSESKVVFTEKTTDGQQIWEME ATVDKDKSQPNMLFVEIPEYRNKHI RTPVKVNFYVINGKRKRSQPQHFTY HPVPAIKTEPTDEYDPTLICSPTHG GLGSQPYYPQHPMVAESPSCLVATM APCQQFRTGLSSPDARYQQQNPAAV LYQRSKSLSPSLLGYQQPALMAAPL SLADAHRSVLVHAGSQGQSSALLHP SPTNQQASPVIHYSPTNQQLRCGSH QEFQHIMYCENFAPGTTRPGPPPVS QGQRLSPGSYPTVIQQQNATSQRAA KNGPPVSDQKEVLPAGVTIKQEQNL DQTYLDDVNEIIRKEFSGPPARNQT TRTRPLEQKLISEEDLAANDILDYK DDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
