Recombinant Human NFKB2 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human NFKB2 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : NFKB2-4888H
Product Overview : NFKB2 MS Standard C13 and N15-labeled recombinant protein (NP_002493) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 96.7 kDa
AA Sequence : Tag(s)MESC YNPGLDGIIE YDDFKLNSSI VEPKEPAPET ADGPYLVIVE QPKQRGFRFR YGCEGPSHGG LPGASSEKGR KTYPTVKICN YEGPAKIEVD LVTHSDPPRA HAHSLVGKQC SELGICAVSV GPKDMTAQFN NLGVLHVTKK NMMGTMIQKL QRQRLRSRPQ GLTEAEQREL EQEAKELKKV MDLSIVRLRF SAFLRASDGS FSLPLKPVIS QPIHDSKSPG ASNLKISRMD KTAGSVRGGD EVYLLCDKVQ KDDIEVRFYE DDENGWQAFG DFSPTDVHKQ YAIVFRTPPY HKMKIERPVT VFLQLKRKRG GDVSDSKQFT YYPLVEDKEE VQRKRRKALP TFSQPFGGGS HMGGGSGGAA GGYGGAGGGG SLGFFPSSLA YSPYQSGAGP MGCYPGGGGG AQMAATVPSR DSGEEAAEPS APSRTPQCEP QAPEMLQRAR EYNARLFGLA QRSARALLDY GVTADARALL AGQRHLLTAQ DENGDTPLHL AIIHGQTSVI EQIVYVIHHA QDLGVVNLTN HLHQTPLHLA VITGQTSVVS FLLRVGADPA LLDRHGDSAM HLALRAGAGA PELLRALLQS GAPAVPQLLH MPDFEGLYPV HLAVRARSPE CLDLLVDSGA EVEATERQGG RTALHLATEM EELGLVTHLV TKLRANVNAR TFAGNTPLHL AAGLGYPTLT RLLLKAGADI HAENEEPLCP LPSPPTSDSD SDSEGPEKDT RSSFRGHTPL DLTCSTKVKT LLLNAAQNTM EPPLTPPSPA GPGLSLGDTA LQNLEQLLDG PEAQGSWAEL AERLGLRSLV DTYRQTTSPS GSLLRSYELA GGDLAGLLEA LSDMGLEEGV RLLRGPETRD KLPSTEVKED SAYGSQSVEQ EAEKLGPPPE PPGGLCHGHP QPQVHTRTRP LEQKLISEED LAANDILDYK DDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : NFKB2 nuclear factor kappa B subunit 2 [ Homo sapiens (human) ]
Official Symbol : NFKB2
Synonyms : NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100); nuclear factor NF-kappa-B p100 subunit; LYT 10; NF kB2; p52; p105; oncogene Lyt-10; DNA-binding factor KBF2; lymphocyte translocation chromosome 10 protein; nuclear factor of kappa light chain gene enhancer in B-cells 2; H2TF1; LYT10; LYT-10; NF-kB2;
Gene ID : 4791
mRNA Refseq : NM_002502
Protein Refseq : NP_002493
MIM : 164012
UniProt ID : Q00653

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