Recombinant Human NGF Protein (Ser122-Val238), Tag Free
Cat.No. : | NGF-0262H |
Product Overview : | Recombinant human NGF (Ser122-Val238)was fused with the No tag and was expressed in Bacillus subtilis. |
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Source : | Bacillus subtilis |
Species : | Human |
Tag : | Non |
Form : | Lyophilized powder/frozen liquid |
Molecular Mass : | 12.87 kDa |
Protein length : | Ser122-Val238 |
Purity : | >90% as determined by SDS-PAGE |
Notes : | For research use only. |
Storage : | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt. |
Storage Buffer : | Supplied as solution form in PBS, pH 7.5 or lyophilized from PBS, pH 7.5. |
Reconstitution : | Reconstitute in sterile water for a stock solution. |
Shipping : | They are shipped out with dry ice/blue ice unless customers require otherwise. |
Gene Name : | NGF nerve growth factor (beta polypeptide) [ Homo sapiens (human) ] |
Official Symbol : | NGF |
Synonyms : | NGF; nerve growth factor (beta polypeptide); NGFB; beta-nerve growth factor; nerve growth factor, beta subunit; HSAN5; Beta-NGF; MGC161426; MGC161428; |
Gene ID : | 4803 |
mRNA Refseq : | NM_002506 |
Protein Refseq : | NP_002497 |
MIM : | 162030 |
UniProt ID : | P01138 |
Products Types
◆ Native Protein | ||
Ngf-51M | Native Mouse Nerve Growth Factor 2.5S | +Inquiry |
Ngf-182M | Active Native Mouse Ngf Protein | +Inquiry |
Ngf-298M | Active Native Mouse Nerve Growth Factor | +Inquiry |
◆ Lysates | ||
NGF-001MCL | Recombinant Mouse NGF cell lysate | +Inquiry |
NGF-001HCL | Recombinant Human NGF cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (3)
Write a reviewHigh catalytic efficiency, high safety and high expression level of the protein make it perform well in many experiments.
The short half-life and high clearance of NGF make it possible to better control the concentration and action time of drugs in the body, so as to better control the therapeutic effect.
This production process of NGF pays attention to the recycling of resources and minimizes waste, which is very consistent with the principle of green production.
Q&As (6)
Ask a questionStudies have shown that NGF protein plays a role in the occurrence and development of pain. It stimulates the growth and survival of sensory neurons and enhances their ability to transmit signals, thereby increasing pain sensation. In addition, NGF can interact with other pain-related molecules to modulate pain perception and tolerance.
There are a variety of drug development treatments that target NGF proteins and their related signaling pathways, including direct administration of NGF proteins, use of their analogues, or drugs that inhibit its degradation. These treatments are in clinical trials and are expected to provide new options for the treatment of neurological disorders.
NGF proteins interact with target cells by binding to their receptors. It binds to TrkA receptors on the surface of target cells, triggering a series of signal transduction mechanisms that ultimately influence the biological behavior of target cells.
In addition to its important role in the nervous system, NGF proteins can also affect the function of other systems. For example, NGF proteins can affect the function of the immune system, involved in inflammatory responses and the development of autoimmune diseases.
The function of NGF protein in glial cells is mainly to regulate its proliferation, differentiation and apoptosis. In addition, NGF promotes the repair and regeneration of damaged neurons by glial cells.
NGF proteins have a variety of biological activities, including promoting neuronal growth, differentiation, survival, and repair of damage, regulating connections and signaling between neurons, and influencing the function of other systems.
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