Recombinant Human NPTX2 Protein, MYC/DDK-tagged, C13 and N15-labeled

• Cat.No.: NPTX2-062H
• Product Overview: NPTX2 MS Standard C13 and N15-labeled recombinant protein (NP_002514) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 46.9 kDa
• AA Sequence: MLALLAASVALAVAAGAQDSPAPGS RFVCTALPPEAVHAGCPLPAMPMQG GAQSPEEELRAAVLQLRETVVQQKE TLGAQREAIRELTGKLARCEGLAGG KARGAGATGKDTMGDLPRDPGHVVE QLSRSLQTLKDRLESLEHQLRANVS NAGLPGDFREVLQQRLGELERQLLR KVAELEDEKSLLHNETSAHRQKTES TLNALLQRVTELERGNSAFKSPDAF KVSLPLRTNYLYGKIKKTLPELYAF TICLWLRSSASPGIGTPFSYAVPGQ ANEIVLIEWGNNPIELLINDKVAQL PLFVSDGKWHHICVTWTTRDGMWEA FQDGEKLGTGENLAPWHPIKPGGVL ILGQEQDTVGGRFDATQAFVGELSQ FNIWDRVLRAQEIVNIANCSTNMPG NIIPWVDNNVDVFGGASKWPVETCE ERLLDLTRTRPLEQKLISEEDLAAN DILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: NPTX2 neuronal pentraxin 2 [ Homo sapiens (human) ]
• Official Symbol: NPTX2
• Synonyms: NPTX2; neuronal pentraxin 2; NARP; NP-II; NP2; neuronal pentraxin-2; apexin; neuronal activity-regulated pentaxin; neuronal pentraxin II
• Gene ID: 4885
• mRNA Refseq: NM_002523
• Protein Refseq: NP_002514
• MIM: 600750
• UniProt ID: P47972