Recombinant Human OSM protein, His-Avi-tagged, Biotinylated
Cat.No. : | OSM-725HB |
Product Overview : | Biotinylated Recombinant Human Oncostatin M Protein is expressed from mammalian with His Tag and Avi Tag at the C-terminal. It contains Ala26-Arg221. |
- Specification
- Gene Information
- Related Products
Description : | OSM is a pleiotropic cytokine that initiates its biological activities by binding to specific cell surface receptors. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDSKS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIFR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration. |
Source : | HEK293 |
Species : | Human |
Tag : | His-Avi |
Form : | Supplied as 0.22μm filtered solution in 20mM PBS,pH7.4 |
Molecular Mass : | The protein has a predicted MW of 25.1 KDa. Due to glycosylation, the protein migrates to 30-40KDa based on Bis-Tris PAGE result. |
Protein length : | Ala26-Arg221 |
Endotoxin : | Less than 0.05EU per μg by the LAL method. |
Purity : | >95% as determined by Tris-Bis PAGE; >95% as determined by HPLC |
Storage : | The product should be stored at -70°C. Please do not repeated freeze-thaw cycles. |
Gene Name : | OSM |
Official Symbol : | OSM |
Synonyms : | MGC20461; oncostatin M; oncostatin-M; OSM |
Gene ID : | 5008 |
mRNA Refseq : | NM_001319108.2 |
Protein Refseq : | NP_001306037.1 |
MIM : | 165095 |
UniProt ID : | P13725 |
Products Types
◆ Recombinant Protein | ||
OSM-43H | Active Recombinant Human OSM Protein, Animal Free | +Inquiry |
Osm-319O | Active Recombinant Rat Osm Protein (215 aa) | +Inquiry |
Osm-320O | Active Recombinant Mouse Osm Protein (182 aa) | +Inquiry |
OSM-4337B | Recombinant Bovine OSM Protein | +Inquiry |
OSM-1589H | Recombinant Human OSM Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
OSM-1766HCL | Recombinant Human OSM cell lysate | +Inquiry |
OSM-1659MCL | Recombinant Mouse OSM cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionOSM can influence cancer progression by altering the tumor microenvironment and affecting tumor cell behavior.
OSM plays a key role in regulating inflammatory and immune responses, modulating cytokine production and immune cell activity.
OSM aids in wound healing and tissue regeneration, promoting cell growth and repair mechanisms.
OSM is implicated in autoimmune diseases, contributing to inflammation and joint damage in conditions like rheumatoid arthritis.
OSM is involved in liver fibrosis, impacting the development and progression of hepatic diseases.
OSM regulates cellular processes like growth, differentiation, and apoptosis, affecting various tissue functions.
Changes in OSM signaling can impact cardiovascular health, influencing disease development and progression.
Customer Reviews (3)
Write a reviewOutstanding protein-protein interaction studies, vital for our projects.
High-quality protein characterization, fundamental for our experiments.
Expertise in peptide synthesis, accelerates our peptide-based research.
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