Recombinant Human PDE4D Protein, His/GST-tagged

• Cat.No.: PDE4D-303H
• Product Overview: Recombinant Human PDE4D(Leu581~Thr809) fused with His/GST tag at N-terminal was expressed in E. coli.

Specification

• Description: This gene encodes one of four mammalian counterparts to the fruit fly 'dunce' gene. The encoded protein has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. This gene uses different promoters to generate multiple alternatively spliced transcript variants that encode functional proteins.
• Source: E. coli
• Species: Human
• Tag: His/GST
• Form: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Molecular Mass: 56.1kDa
• Protein length: Leu581~Thr809
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: > 93%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
  If bio-activity of the protein is needed, please check active protein.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: PDE4D phosphodiesterase 4D, cAMP-specific [ Homo sapiens ]
• Official Symbol: PDE4D
• Synonyms: PDE4D; phosphodiesterase 4D, cAMP-specific; DPDE3, phosphodiesterase 4D, cAMP specific (dunce (Drosophila) homolog phosphodiesterase E3); cAMP-specific 3,5-cyclic phosphodiesterase 4D; phosphodiesterase E3 dunce homolog (Drosophila); cAMP-specific phosphodiesterase PDE4D6; phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila); DPDE3; PDE43; STRK1; HSPDE4D; PDE4DN2; FLJ97311; DKFZp686M11213
• Gene ID: 5144
• mRNA Refseq: NM_001104631
• Protein Refseq: NP_001098101
• MIM: 600129
• UniProt ID: Q08499