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Recombinant Human PHLDA3 protein, Myc/DDK-tagged

Cat.No. : PHLDA3-1692H
Product Overview : Recombinant Human PHLDA3 protein, fused with Myc/DDK-tagged, was expressed in HEK293T and captured through anti-DDK affinity column followed by conventional chromatography steps.
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  • Gene Information
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Description : p53/TP53-regulated repressor of Akt/AKT1 signaling. Represses AKT1 by preventing AKT1-binding to membrane lipids, thereby inhibiting AKT1 translocation to the cellular membrane and activation. Contributes to p53/TP53-dependent apoptosis by repressing AKT1 activity. Its direct transcription regulation by p53/TP53 may explain how p53/TP53 can negatively regulate AKT1. May act as a tumor suppressor.
Source : HEK293
Species : Human
Tag : Myc/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 13.7 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining.
Concentration : >50 μg/mL as determined by microplate BCA method.
Gene Name : PHLDA3
Official Symbol : PHLDA3
Synonyms : TIH1
Gene ID : 23612
mRNA Refseq : NM_012396.5
Protein Refseq : NP_036528.1
MIM : 607054
UniProt ID : Q9Y5J5

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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12/23/2020

    Incorporating protein reagents minimizes repetitive operations, thus boosting experimental efficiency.

    02/25/2018

      Manufacturers of protein reagents adhere to scientific rigor, ensuring the reliability of their products.

      06/01/2017

        The usage method of protein reagents is versatile, suitable for analyzing different types of samples.

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