Recombinant Human PLXNA1 Protein (986-1152 aa), His-tagged

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Recombinant Human PLXNA1 Protein (986-1152 aa), His-tagged

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Cat.No. : PLXNA1-1720H
Product Overview : Recombinant Human PLXNA1 Protein (986-1152 aa) is produced by Yeast expression system. This protein is fused with a 6xHis tag at the N-terminal. Research Area: Neuroscience. Protein Description: Partial.
Description : Coreceptor for SA3A, SA3C, SA3F and SA6D. Necessary for signaling by class 3 saphorins and subsequent rodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 saphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific saphorins, and its Cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm.
Source : Yeast
Species : Human
Tag : His
Form : Tris-based buffer,50% glycerol
Molecular Mass : 20.3 kDa
Protein length : 986-1152 aa
AA Sequence : LNAGSDVAVS VGGRPCSFSW RNSREIRCLT PPGQSPGSAP IIININRAQL TNPEVKYNYT EDPTILRIDP EWSINSGGTL LTVTGTNLAT VREPRIRAKY GGIERENGCL VYNDTTMVCR APSVANPVRS PPELGERPDE LGFVMDNVRS LLVLNSTSFL YYPDPVL
Purity : > 90% as determined by SDS-PAGE.
Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
Storage : The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
Concentration : A hardcopy of COA with reconstitution instruction is sent along with the products.
Figure :

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Gene Name : PLXNA1 plexin A1 [ Homo sapiens ]
Official Symbol : PLXNA1
Synonyms : PLXNA1; plexin A1; PLXN1; plexin-A1; NOV; plexin 1; NOVP; PLEXIN-A1; DKFZp761P19121;
Gene ID : 5361
mRNA Refseq : NM_032242
Protein Refseq : NP_115618
MIM : 601055
UniProt ID : Q9UIW2

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