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Recombinant Human PRAME Protein (1-509 aa), His-tagged

Cat.No. : PRAME-1492H
Product Overview : Recombinant Human PRAME Protein (1-509 aa) is produced by Yeast expression system. This protein is fused with a 6xHis tag at the N-terminal. Research Area: Apoptosis. Protein Description: Full Length.
  • Specification
  • Gene Information
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Description : Functions as a transcriptional repressor, inhibiting the signaling of retinoic acid through the retinoic acid receptors RARA, RARB and RARG. Prevents retinoic acid-induced cell proliferation arrest, differentiation and apoptosis.
Source : Yeast
Species : Human
Tag : His
Form : Tris-based buffer,50% glycerol
Molecular Mass : 59.9 kDa
Protein length : 1-509 aa
AA Sequence : MERRRLWGSIQSRYISMSVWTSPRR LVELAGQSLLKDEALAIAALELLPR ELFPPLFMAAFDGRHSQTLKAMVQA WPFTCLPLGVLMKGQHLHLETFKAV LDGLDVLLAQEVRPRRWKLQVLDLR KNSHQDFWTVWSGNRASLYSFPEPE AAQPMTKKRKVDGLSTEAEQPFIPV EVLVDLFLKEGACDELFSYLIEKVK RKKNVLRLCCKKLKIFAMPMQDIKM ILKMVQLDSIEDLEVTCTWKLPTLA KFSPYLGQMINLRRLLLSHIHASSY ISPEKEEQYIAQFTSQFLSLQCLQA LYVDSLFFLRGRLDQLLRHVMNPLE TLSITNCRLSEGDVMHLSQSPSVSQ LSVLSLSGVMLTDVSPEPLQALLER ASATLQDLVFDECGITDDQLLALLP SLSHCSQLTTLSFYGNSISISALQS LLQHLIGLSNLTHVLYPVPLESYED IHGTLHLERLAYLHARLRELLCELG RPSMVWLSANPCPHCGDRTFYDPEP ILCPCFMPN
Purity : > 90% as determined by SDS-PAGE.
Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
Storage : The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
Concentration : A hardcopy of COA with reconstitution instruction is sent along with the products.
Gene Name : PRAME preferentially expressed antigen in melanoma [ Homo sapiens ]
Official Symbol : PRAME
Synonyms : PRAME; MAPE; CT130; OIP-4; OIP4;
Gene ID : 23532
mRNA Refseq : NM_006115
Protein Refseq : NP_006106
MIM : 606021
UniProt ID : P78395

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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