Recombinant Human RARA protein, GST/His-tagged

• Cat.No.: RARA-170H
• Product Overview: Recombinant Human RARA, transcript variant 1, fused with GST tag at N-terminal and His tag at C-terminal was expressed in E. coli.

Specification

• Description: This gene represents a nuclear retinoic acid receptor. The encoded protein, retinoic acid receptor alpha, regulates transcription in a ligand-dependent manner. This gene has been implicated in regulation of development, differentiation, apoptosis, granulopoeisis, and transcription of clock genes. Translocations between this locus and several other loci have been associated with acute promyelocytic leukemia. Alternatively spliced transcript variants have been found for this locus.
• Source: E. coli
• Species: Human
• Tag: GST/His
• Form: 25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1% Sarkosyl.
• Molecular Mass: 78.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: RARA retinoic acid receptor, alpha [ Homo sapiens ]
• Official Symbol: RARA
• Synonyms: RARA; retinoic acid receptor, alpha; retinoic acid receptor alpha; NR1B1; RAR; RAR-alpha; retinoic acid receptor, alpha polypeptide; nuclear receptor subfamily 1 group B member 1; retinoic acid nuclear receptor alpha variant 1; retinoic acid nuclear receptor alpha variant 2; nucleophosmin-retinoic acid receptor alpha fusion protein NPM-RAR long form
• Gene ID: 5914
• mRNA Refseq: NM_000964
• Protein Refseq: NP_000955
• MIM: 180240
• UniProt ID: P10276