Recombinant Human ROR1 Protein, DDK/His-tagged
Cat.No. : | ROR1-755H |
Product Overview : | Recombinant Human ROR1(Gln30-Lys393), transcript variant 2, fused with DDK/His tag at C-terminal was expressed in HEK293 cells. |
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Description : | This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Source : | HEK293 cells |
Species : | Human |
Tag : | His&Flag |
Form : | 1 x PBS, pH7.4, 10% glycerol |
Molecular Mass : | 44 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | ROR1 receptor tyrosine kinase-like orphan receptor 1 [ Homo sapiens ] |
Official Symbol : | ROR1 |
Synonyms : | ROR1; receptor tyrosine kinase-like orphan receptor 1; NTRKR1; tyrosine-protein kinase transmembrane receptor ROR1; neurotrophic tyrosine kinase receptor-related 1; neurotrophic tyrosine kinase, receptor-related 1; dJ537F10.1; MGC99659; |
Gene ID : | 4919 |
mRNA Refseq : | NM_001083592 |
Protein Refseq : | NP_001077061 |
MIM : | 602336 |
UniProt ID : | Q01973 |
Products Types
◆ Recombinant Protein | ||
ROR1-512H | Recombinant Human ROR1 Protein, His-tagged | +Inquiry |
ROR1-429H | Recombinant Full Length Human ROR1 Protein, Fc-tagged | +Inquiry |
Ror1-513M | Recombinant Mouse Ror1 Protein, His-tagged | +Inquiry |
ROR1-426H | Recombinant Human ROR1 Protein, His and Strep-tagged | +Inquiry |
Ror1-430M | Recombinant Full Length Mouse Ror1 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
ROR1-002HCL | Recombinant Human ROR1 cell lysate | +Inquiry |
ROR1-001HCL | Recombinant Human ROR1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (3)
Write a reviewCustomer service promptly feedback my requests, technical staff timely solve the problems that arise.
Excellent after-sales service, solving many experimental problems.
Fast and timely shipment helped me to get satisfactory experimental results in short time.
Q&As (4)
Ask a questionROR1 is barely expressed in normal, differentiated and mature tissues, but is highly expressed in tumor tissues.
Inhibit the expression of ROR1 can reduce the proliferation and migration ability of tumor cells.
ROR1 is involved in the regulation of cell metabolism, proliferation, apoptosis, and differentiation.
ROR1 is involved in the study of breast, lung and ovarian cancers.
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