Recombinant Human RS1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: RS1-5226H
• Product Overview: RS1 MS Standard C13 and N15-labeled recombinant protein (NP_000321) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes an extracellular protein that plays a crucial role in the cellular organization of the retina. The encoded protein is assembled and secreted from photoreceptors and bipolar cells as a homo-oligomeric protein complex. Mutations in this gene are responsible for X-linked retinoschisis, a common, early-onset macular degeneration in males that results in a splitting of the inner layers of the retina and severe loss in vision.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 25.59 kDa
• AA Sequence: MSRKIEGFLLLLLFGYEATLGLSST EDEGEDPWYQKACKCDCQGGPNALW SAGATSLDCIPECPYHKPLGFESGE VTPDQITCSNPEQYVGWYSSWTANK ARLNSQGFGCAWLSKFQDSSQWLQI DLKEIKVISGILTQGRCDIDEWMTK YSVQYRTDERLNWIYYKDQTGNNRV FYGNSDRTSTVQNLLRPPIISRFIR LIPLGWHVRIAIRMELLECVSKCAT RTRPLEQKLISEEDLAANDILDYKD DDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: RS1 retinoschisin 1 [ Homo sapiens (human) ]
• Official Symbol: RS1
• Synonyms: RS1; retinoschisin 1; RS; XLRS1; retinoschisin; X-linked juvenile retinoschisis protein
• Gene ID: 6247
• mRNA Refseq: NM_000330
• Protein Refseq: NP_000321
• MIM: 300839
• UniProt ID: O15537