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Recombinant Human S100B Protein

Cat.No. : S100B-0052H
Product Overview : Recombinant Human S100B Protein without tag was expressed in HEK293.
  • Specification
  • Gene Information
  • Related Products
Description : The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.
Source : HEK293 cells
Species : Human
Applications : ELISA, CLIA, CG
Notes : For research use only, not for use in diagnostic procedure.
Storage : Short term (up to 7 days) store at 2–8 centigrade. Long term, store at - 20 centigrade. Avoid multiple freeze/thaw cycles.
Storage Buffer : Supplied as a 0.2 μm filtered solution of PBS, pH7.4
Gene Name : S100B S100 calcium binding protein B [ Homo sapiens (human) ]
Official Symbol : S100B
Synonyms : S100B; S100 calcium binding protein B; S100 calcium binding protein, beta (neural); protein S100-B; S100beta; S-100 protein subunit beta; S-100 calcium-binding protein, beta chain; S100 calcium-binding protein, beta (neural); NEF; S100; S100-B;
Gene ID : 6285
mRNA Refseq : NM_006272
Protein Refseq : NP_006263
MIM : 176990
UniProt ID : P04271

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How does S100B help in the diagnosis of traumatic brain injury (TBI)? 01/29/2023

Elevated S100B levels in the blood can indicate TBI, and its measurement can aid in TBI diagnosis and severity assessment.

What conditions can S100B be used to diagnose? 01/11/2023

S100B can be used to diagnose brain injuries, such as traumatic brain injury and stroke.

How is S100B measured in clinical settings? 02/24/2020

S100B levels are typically measured through a blood test.

What precautions should be taken when interpreting S100B results? 02/02/2017

Results should be interpreted in the context of the patient's clinical history and other diagnostic tests.

How is S100B used in the context of neurodegenerative diseases? 02/07/2016

S100B may help in monitoring disease progression and severity in conditions like Alzheimer's disease.

Customer Reviews (3)

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Reviews
03/15/2022

    One major advantage of S100B protein is its ability to contribute to the understanding of diseases related to aberrant cell cycle regulation, including cancer.

    09/29/2019

      The S100B protein demonstrates exceptional quality, making it an ideal candidate to fulfill my experimental requirements.

      10/23/2018

        The manufacturer of S100B protein plays a crucial role in supporting my research efforts.

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