| Description : |
The protein encoded by this gene is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. This gene product is found to be an important cellular factor for HIV-1 gene expression and viral replication. It also associates transiently with U6 and U4/U6 snRNPs during the recycling phase of the spliceosome cycle. This encoded protein is thought to be involved in the regulation of mRNA splicing. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
109.9 kDa |
| AA Sequence : |
MATAAETSASEPEAESKAGPKADGE EDEVKAARTRRKVLSRAVAAATYKT MGPAWDQQEEGVSESDGDEYAMASS AESSPGEYEWEYDEEEEKNQLEIER LEEQLSINVYDYNCHVDLIRLLRLE GELTKVRMARQKMSEIFPLTEELWL EWLHDEISMAQDGLDREHVYDLFEK AVKDYICPNIWLEYGQYSVGGIGQK GGLEKVRSVFERALSSVGLHMTKGL ALWEAYREFESAIVEAARLEKVHSL FRRQLAIPLYDMEATFAEYEEWSED PIPESVIQNYNKALQQLEKYKPYEE ALLQAEAPRLAEYQAYIDFEMKIGD PARIQLIFERALVENCLVPDLWIRY SQYLDRQLKVKDLVLSVHNRAIRNC PWTVALWSRYLLAMERHGVDHQVIS VTFEKALNAGFIQATDYVEIWQAYL DYLRRRVDFKQDSSKELEELRAAFT RALEYLKQEVEERFNESGDPSCVIM QNWARIEARLCNNMQKARELWDSIM TRGNAKYANMWLEYYNLERAHGDTQ HCRKALHRAVQCTSDYPEHVCEVLL TMERTEGSLEDWDIAVQKTETRLAR VNEQRMKAAEKEAALVQQEEEKAEQ RKRARAEKKALKKKKKIRGPEKRGA DEDDEKEWGDDEEEQPSKRRRVENS IPAAGETQNVEVAAGPAGKCAAVDV EPPSKQKEKAASLKRDMPKVLHDSS KDSITVFVSNLPYSMQEPDTKLRPL FEACGEVVQIRPIFSNRGDFRGYCY VEFKEEKSALQALEMDRKSVEGRPM FVSPCVDKSKNPDFKVFRYSTSLEK HKLFISGLPFSCTKEELEEICKAHG TVKDLRLVTNRAGKPKGLAYVEYEN ESQASQAVMKMDGMTIKENIIKVAI SNPPQRKVPEKPETRKAPGGPMLLP QTYGARGKGRTQLSLLPRALQRPSA AAPQAENGPAAAPAVAAPAATEAPK MSNADFAKLFLRKTRTRPLEQKLIS EEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
