Recombinant Human SMAD2 protein, T7/His-tagged

Cat.No. : SMAD2-118H
Product Overview : Recombinant human SMAD2 fused with T7/His/TEV cleavage site 29aa Tag at N-terminal was expressed in E. coli.
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Source : E. coli
Species : Human
Tag : T7/His
Form : 0.2 mg/ml, sterile-filtered, in 20 mM pH 8.0 Tris-HCl Buffer, with proprietary formulation of NaCl, KCl, EDTA, arginine, DTT and Glycerol.
AA Sequence : MASMTGGQQMGRGHHHHHHGNLYFQ GGEFSSILPFTPPVVKRLLGWKKSA GGSGGAGGGEQNGQEEKWCEKAVKS LVKKLKKTGRLDELEKAITTQNCNT KCVTIPSTCSEIWGLSTPNTIDQWD TTGLYSFSEQTRSLDGRLQVSHRKG LPHVIYCRLWRWPDLHSHHELKAIE NCEYAFNLKKDEVCVNPYHYQRVET PVLPPVLVPRHTEILTELPPLDDYT HSIPENTNFPAGIEPQSNYIPETPP PGYISEDGETSDQQLNQSMDTGSPA ELSPTTLSPVNHSLDLQPVTYSEPA FWCSIAYYELNQRVGETFHASQPSL TVDGFTDPSNSERFCLGLLSNVNRN ATVEMTRRHIGRGVRLYYIGGEVFA ECLSDSAIFVQSPNCNQRYGWHPAT VCKIPPGCNLKIFNNQEFAALLAQS VNQGFEAVYQLTRMCTIRMSFVKGW GAEYRRQTVTSTPCWIELHLNGPLQ WLDKVLTQMGSPSVRCSSMS
Purity : >90% by SDS-PAGE
Applications : 1. May be used for human SMAD2 functional regulation study in vitro,2. May be used as specific substrate protein for kinase and ubiquitin enzymes.3. May be used for specific antibody production.
Storage : Keep at -20°C for long term storage. Product is stable at 4 °C for at least 30 days.
Gene Name : SMAD2 SMAD family member 2 [ Homo sapiens ]
Official Symbol : SMAD2
Synonyms : SMAD2; SMAD family member 2; MAD, mothers against decapentaplegic homolog 2 (Drosophila) , MADH2, SMAD, mothers against DPP homolog 2 (Drosophila)
Gene ID : 4087
mRNA Refseq : NM_001003652
Protein Refseq : NP_001003652
MIM : 601366
UniProt ID : Q15796
Chromosome Location : 18q21
Pathway : Adherens junction, organism-specific biosystem; Adherens junction, conserved biosystem; Alpha6-Beta4 Integrin Signaling Pathway, organism-specific biosystem; Cell cycle, organism-specific biosystem; Cell cycle, conserved biosystem; Chagas disease (American trypanosomiasis), organism-specific biosystem; Chagas disease (American trypanosomiasis), conserved biosystem;
Function : contributes_to DNA binding; I-SMAD binding; R-SMAD binding; SMAD binding; activating transcription factor binding; chromatin binding; co-SMAD binding; double-stranded DNA binding; phosphatase binding; protein binding; sequence-specific DNA binding transcription factor activity; contributes_to sequence-specific DNA binding transcription factor activity; transcription factor binding; transforming growth factor beta receptor binding; transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity; type I transforming growth factor beta receptor binding; ubiquitin protein ligase binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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