Active Recombinant Human ST6GAL1 Protein

• Cat.No.: ST6GAL1-28H
• Product Overview: Recombinant human Beta-galactoside alpha-2,6-sialyltransferase 1 (ST6Gal I) without tag was expressed in human HEK 293 cells as a glycoprotein with a calculated molecular mass of 43.5 kDa (amino acids 27-406).

Specification

• Description: This gene encodes a member of glycosyltransferase family 29. The encoded protein is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The protein, which is normally found in the Golgi but can be proteolytically processed to a soluble form, is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CD75, and CD76. This gene has been incorrectly referred to as CD75. Alternative splicing results in multiple transcript variants.
• Source: HEK293
• Species: Human
• Form: Lyophilized powder
• Bio-activity: ≥300 units/mg protein
• Molecular Mass: 43.5 kDa
• Protein length: 27-406
• Purity: ≥ 95% (The specific activity of ST6Gal I is measured by its ability to transfer sialic acid from CMP-NANA to asialofetuin, SDS-PAGE)
• Unit Definition: One unit is defined as the amount of enzyme required to transfer 1.0 nanomole of sialic acid from CMP-NANA to asialofetuin per minute at pH 6.0, 37 centigrade.
• Storage: At -20 centigrade.
• Shipping: Ambient

Gene Information

• Gene Name: ST6GAL1 ST6 beta-galactoside alpha-2,6-sialyltransferase 1 [ Homo sapiens (human) ]
• Official Symbol: ST6GAL1
• Synonyms: ST6GAL1; ST6 beta-galactoside alpha-2,6-sialyltransferase 1; ST6N; SIAT1; ST6GalI; beta-galactoside alpha-2,6-sialyltransferase 1; B-cell antigen CD75; CMP-N-acetylneuraminate beta-galactosamide alpha-2,6-sialyltransferase; CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1; ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1; ST6 beta-galactosamide alpha-2,6-sialyltranferase 1; ST6Gal I; alpha 2,6-ST 1; sialyltransferase 1 (beta-galactoside alpha-2,6-sialyltransferase); EC 2.4.99.1
• Gene ID: 6480
• mRNA Refseq: NM_173217
• Protein Refseq: NP_775324
• MIM: 109675
• UniProt ID: P15907