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Recombinant Human STAT1 protein, GST-tagged

Cat.No. : STAT1-2996H
Product Overview : Recombinant Human STAT1 protein(2-230 aa), fused with GST tag, was expressed in E.coli.
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Source : E.coli
Species : Human
Tag : GST
Form : The purified protein was Lyophilized from sterile PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8.). 5 % trehalose and 5 % mannitol are added as protectant before lyophilization. The elution buffer contain 100mM GSH.
Protein Length : 2-230 aa
AA Sequence : SQWYELQQLDSKFLEQVHQLYDDSF PMEIRQYLAQWLEKQDWEHAANDVS FATIRFHDLLSQLDDQYSRFSLENN FLLQHNIRKSKRNLQDNFQEDPIQM SMIIYSCLKEERKILENAQRFNQAQ SGNIQSTVMLDKQKELDSKVRNVKD KVMCIEHEIKSLEDLQDEYDFKCKT LQNREHETNGVAKSDQKQEQLLLKK MYLMLDNKRKEVVHKIIELLNVTEL TQNA
Purity : 95%, by SDS-PAGE with Coomassie Brilliant Blue staining.
Storage : Short-term storage: Store at 2-8°C for (1-2 weeks).
Long-term storage: Aliquot and store at -20°C to -80°C for up to 3 months, buffer containing 50% glycerol is recommended for reconstitution. Avoid repeat freeze-thaw cycles.
Reconstitution : Reconstitute at 0.25 µg/μl in 200 μl sterile water for short-term storage.
Reconstitution with 200 μl 50% glycerol solution is recommended for longer term storage.
Gene Name : STAT1 signal transducer and activator of transcription 1, 91kDa [ Homo sapiens ]
Official Symbol : STAT1
Synonyms : STAT1; signal transducer and activator of transcription 1, 91kDa; signal transducer and activator of transcription 1, 91kD; signal transducer and activator of transcription 1-alpha/beta; ISGF 3; STAT91; transcription factor ISGF 3 components p91/p84; transcription factor ISGF-3 components p91/p84; signal transducer and activator of transcription-1; CANDF7; ISGF-3; DKFZp686B04100;
Gene ID : 6772
mRNA Refseq : NM_007315
Protein Refseq : NP_009330
MIM : 600555
UniProt ID : P42224

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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What is the function of the STAT1 protein? 12/23/2019

STAT1 is a signal transduction and transcriptional activator involved in regulating a variety of biological processes such as cell growth, differentiation, apoptosis, and immune response.

Are mutations in genes associated with the STAT1 protein related to human disease? 09/21/2019

Mutations in the STAT1 gene have been found to be associated with a variety of diseases, including autoimmune diseases, primary immunodeficiency diseases, and malignant tumors.

What is the signaling pathway of STAT1 protein in immune cells? 09/01/2019

The STAT1 protein is primarily activated by the JAK-STAT signaling pathway. When activated by the receptor, JAK kinase phosphorylates the STAT1 protein, allowing it to form dimers and enter the nucleus to regulate transcription of related genes.

In which diseases does the STAT1 protein play an important role in the development of diseases? 07/16/2019

The STAT1 protein plays an important role in many diseases, including tumors, immune-related diseases (such as immunodeficiency diseases, autoimmune diseases), infectious diseases (such as viral infections), etc.

Are there activators or inhibitors of the STAT1 protein? 06/19/2019

Some activators or inhibitors of the STAT1 protein have been identified. These compounds can be used to study the function of the STAT1 protein and the development of disease treatments.

Is the STAT1 protein involved in the immune response to viral infection? 02/24/2019

The STAT1 protein plays an important role in viral infection. It mediates interferon signaling, promotes antiviral immune responses, and inhibits viral replication and transmission.

Customer Reviews (3)

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04/22/2020

    It is well suited for our laboratory to induce specific immune responses.

    11/26/2019

      It has great application potential and performs well in all aspects.

      04/16/2019

        This protein has high yield and high purity, which greatly improves our production efficiency.

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