Recombinant Human STAT3, His-tagged
Cat.No. : | STAT3-2176H |
Product Overview : | Recombinant Human STAT3(Met1-Asn175), transcript variant 3, fused with C-terminal 6His tag, was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | Signal Transducer and Activator of Transcription 3 (STAT3) belongs to the transcription factor STAT family. STAT3 contains one SH2 domain and is a transcription factor expressed in most cell types. STAT3 is activated by multiple cytokines and growth factors including: IFN-a, IL-10, IL-6, IL-11, IL-12, IL-2, EGF etc. STAT3 functions as signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. In addition, STAT3 may also mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4 |
AA Sequence : | MAQWNQLQQLDTRYLEQLHQLYSDS FPMELRQFLAPWIESQDWAYAASKE SHATLVFHNLLGEID QQYSRFLQESNVLYQHNLRRIKQFL QSRYLEKPMEIARIVARCLWEESRL LQTAATAAQQGGQAN HPTAAVVTEKQQMLEQHLQDVRKRV QDLEQKMKVVENLQDDFDFNLEHHH HHH |
Endotoxin : | Less than 0.1 ng/µg (1 IEU/µg). |
Purity : | Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. |
Usage : | FOR RESEARCH USE ONLY |
Storage : | Lyophilized protein should be stored at < -20 centigrade, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7 centigrade for 2-7 days.Aliquots of reconstituted samples are stable at < -20 centigrade for 3 months. |
Reconstitution : | Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Gene Name : | STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) [ Homo sapiens ] |
Official Symbol : | STAT3 |
Synonyms : | APRF; HIES; ADMIO; signal transducer and activator of transcription 3; DNA-binding protein APRF; acute-phase response factor |
Gene ID : | 6774 |
mRNA Refseq : | NM_213662 |
Protein Refseq : | NP_998827 |
MIM : | 102582 |
UniProt ID : | P40763 |
Chromosome Location : | 17q21.31 |
Pathway : | AGE/RAGE pathway, organism-specific biosystem; Acute myeloid leukemia, conserved biosystem; Cellular responses to stress, organism-specific biosystem |
Function : | CCR5 chemokine receptor binding; DNA binding; protein binding |
Products Types
◆ Recombinant Protein | ||
STAT3-8786M | Recombinant Mouse STAT3 Protein, His (Fc)-Avi-tagged | +Inquiry |
STAT3-001H | Recombinant Human STAT3 Protein, His-tagged | +Inquiry |
STAT3-2837H | Recombinant Human STAT3 Protein, His-tagged | +Inquiry |
STAT3-5437R | Recombinant Rat STAT3 Protein, His (Fc)-Avi-tagged | +Inquiry |
Stat3-2107R | Recombinant Rat Stat3 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
STAT3-1418HCL | Recombinant Human STAT3 293 Cell Lysate | +Inquiry |
STAT3-1417HCL | Recombinant Human STAT3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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