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Recombinant Human TDGF1 protein(Met1-Thr172), hFc-tagged

Cat.No. : TDGF1-1048H
Product Overview : Recombinant Human TDGF1 (NP_003203.1) (Met1-Thr172) was expressed in HEK293 with the Fc region of Human IgG1 at the C-terminus.
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Source : HEK293
Species : Human
Tag : C-hFc
Protein length : Met1-Thr172
Form : Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Bio-activity : Measured by its binding ability in a functional ELISA. Immobilized ALK4-His at 10 μg/mL (100 μL/well) can bind TDGF1-Fc, the EC50 of human TDGF1-Fc is 6.0-14 ng/mL.
Molecular Mass : The recombinant human TDGF1 consists of 380 amino acids and predicts a molecular mass of 42.7 kDa.
Endotoxin : < 1.0 EU per μg protein as determined by the LAL method.
Purity : > 95 % as determined by SDS-PAGE.
Storage : Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
Gene Name : TDGF1 teratocarcinoma-derived growth factor 1 [ Homo sapiens ]
Official Symbol : TDGF1
Synonyms : TDGF1; teratocarcinoma-derived growth factor 1; CR; CRIPTO; Cripto 1; cripto-1 growth factor; epidermal growth factor-like cripto protein CR1; CRGF;
Gene ID : 6997
mRNA Refseq : NM_001174136
Protein Refseq : NP_001167607
UniProt ID : P13385

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Is TDGF1 associated with any genetic disorders? 01/26/2021

Mutations in the TDGF1 gene have been linked to certain congenital disorders. Understanding these genetic associations can provide insights into the underlying mechanisms of these conditions.

How does TDGF1 influence neurodevelopment? 02/11/2020

TDGF1 has been found to play a role in neural development. It is involved in the specification of neural cell fate and the formation of the neural tube during embryogenesis.

Can TDGF1 be a target for drug development? 06/27/2019

Yes, efforts are underway to develop drugs that modulate TDGF1 activity. Targeting TDGF1 could potentially lead to novel therapies for conditions related to cell growth and differentiation.

In what ways does TDGF1 contribute to stem cell biology? 06/04/2019

TDGF1 is involved in the maintenance of pluripotency in embryonic stem cells. Understanding its role could enhance our ability to control and manipulate stem cells for therapeutic purposes.

How can TDGF1 be utilized in cancer diagnostics? 10/09/2016

Researchers are exploring the use of TDGF1 as a biomarker for certain cancers. Detection of elevated TDGF1 levels in patient samples may aid in early cancer diagnosis.

Customer Reviews (3)

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01/13/2020

    the manufacturer can assist in sourcing complementary reagents and tools, such as specific antibodies or detection systems, to complement the use of TDGF1 protein in trials.

    03/26/2018

      manufacturers often have a wealth of knowledge and expertise in the field of TDGF1 protein research.

      08/29/2017

        They may offer educational resources such as technical guides, protocols, and application notes, which can aid researchers in understanding the principles, techniques, and potential applications of TDGF1 protein in their studies.

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