Recombinant Human TEAD4 Protein (74-434 aa), His-SUMO-tagged
Cat.No. : | TEAD4-1005H |
Product Overview : | Recombinant Human TEAD4 Protein (74-434 aa) is produced by E. coli expression system. This protein is fused with a 6xHis-SUMO tag at the N-terminal. Research Area: Transcription. Protein Description: Partial. |
- Specification
- Gene Information
- Related Products
Description : | Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (T) induction. Binds specifically and non-cooperatively to the Sph and GT-IIC 'enhansons' (5'-GTGGAATGT-3') and activates transcription. Binds to the M-CAT motif. |
Source : | E. coli |
Species : | Human |
Tag : | His-SUMO |
Form : | Tris-based buffer, 50% glycerol |
Molecular Mass : | 56.7 kDa |
Protein length : | 74-434 aa |
AA Sequence : | MYGRNELIARYIKLRTGKTRTRKQV SSHIQVLARRKAREIQAKLKDQAAK DKALQSMAAMSSAQIISATAFHSSM ALARGPGRPAVSGFWQGALPGQAGT SHDVKPFSQQTYAVQPPLPLPGFES PAGPAPSPSAPPAPPWQGRSVASSK LWMLEFSAFLEQQQDPDTYNKHLFV HIGQSSPSYSDPYLEAVDIRQIYDK FPEKKGGLKDLFERGPSNAFFLVKF WADLNTNIEDEGSSFYGVSSQYESP ENMIITCSTKVCSFGKQVVEKVETE YARYENGHYSYRIHRSPLCEYMINF IHKLKHLPEKYMMNSVLENFTILQV VTNRDTQETLLCIAYVFEVSASEHG AQHHIYRLVKE |
Purity : | > 90% as determined by SDS-PAGE. |
Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
Storage : | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
Concentration : | A hardcopy of COA with concentration instruction is sent along with the products. |
Gene Name : | TEAD4 TEA domain family member 4 [ Homo sapiens ] |
Official Symbol : | TEAD4 |
Synonyms : | TEAD4; TCF13L1; EFTR 2; RTEF 1; TEF 3; TEFR 1; TEF3; RTEF1; TEF-3; EFTR-2; TEFR-1; hRTEF-1B; MGC9014; |
Gene ID : | 7004 |
mRNA Refseq : | NM_003213 |
Protein Refseq : | NP_003204 |
MIM : | 601714 |
UniProt ID : | Q15561 |
Products Types
◆ Recombinant Protein | ||
TEAD4-9116M | Recombinant Mouse TEAD4 Protein, His (Fc)-Avi-tagged | +Inquiry |
TEAD4-16620M | Recombinant Mouse TEAD4 Protein | +Inquiry |
TEAD4-6335C | Recombinant Chicken TEAD4 | +Inquiry |
TEAD4-1102C | Recombinant Chicken TEAD4 | +Inquiry |
Tead4-4587M | Recombinant Mouse Tead4 protein | +Inquiry |
◆ Lysates | ||
TEAD4-1758HCL | Recombinant Human TEAD4 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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