Recombinant Human Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein, Zeta Polypeptide
Cat.No. : | YWHAZ-4901H |
Product Overview : | Recombinant full-length human tag-free YWHAZ was expressed in E. coli cells. |
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Cat. No. : | YWHAZ-4901H |
Description : | YWHAZ (also known as tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide) is a member of the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. YWHAZ protein plays a key role in cancer biology by being an important regulator of major cellular processes such as proliferation, differentiation, senescence and apoptosis. YWHAZ protein has been shown to interact with the IRS1 protein, suggesting a role for this protein in regulating insulin sensitivity by interrupting the association between the insulin receptor and IRS1. |
Applications : | Western Blot |
Molecular Weight : | 29kDa |
Expression System : | E.coli |
Species : | Human |
Form : | Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Purity : | >95 % |
Concentration : | 0.2ug/ul |
Sequences : | Full-length |
Storage : | Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Pathways : | Adaptive Immunity Signaling; Alpha6-Beta4 Integrin Signaling Pathway; Calcium Regulation in the Cardiac Cell; Cell cycle; Class I PI3K signaling events mediated by Akt; Cytokine Signaling in Immune system; Destabilization of mRNA by KSRP; ErbB1 downstream signaling; Formation of Platelet plug; FoxO family signaling; GP1b-IX-V activation signalling; Hemostasis; IGF1 pathway; IL-3 Signaling Pathway; IL-5 Signaling Pathway |
Tag : | Non |
Gene Name : | YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide [ Homo sapiens ] |
Official Symbol : | YWHAZ |
Synonyms : | YWHAZ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide; KCIP-1; MGC111427; MGC126532; MGC138156; phospholipase A2; 14-3-3 zeta; 14-3-3 protein/cytosolic phospholipase A2; Protein kinase C inhibitor protein 1; protein kinase C inhibitor protein-1; tyrosine 3/tryptophan 5 -monooxygenase activation protein, zeta polypeptide; OTTHUMP00000165851; OTTHUMP00000165852; OTTHUMP00000165854; OTTHUMP00000165858; OTTHUMP00000165859; OTTHUMP00000165860; YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide |
Gene ID : | 7534 |
mRNA Refseq : | NM_001135699 |
Protein Refseq : | NP_001129171 |
MIM : | 601288 |
UniProt ID : | P63104 |
Chromosome Location : | 8q23.1 |
Function : | protein binding; protein domain specific binding; transcription factor binding |
Products Types
◆ Recombinant Protein | ||
YWHAZ-226H | Recombinant Human YWHAZ Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
YWHAZ-6298R | Recombinant Rat YWHAZ Protein, His (Fc)-Avi-tagged | +Inquiry |
YWHAZ-10271M | Recombinant Mouse YWHAZ Protein, His (Fc)-Avi-tagged | +Inquiry |
YWHAZ-5062R | Recombinant Rhesus Macaque YWHAZ Protein, His (Fc)-Avi-tagged | +Inquiry |
YWHAZ-2381H | Recombinant Human YWHAZ Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
YWHAZ-229HCL | Recombinant Human YWHAZ 293 Cell Lysate | +Inquiry |
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Not For Human Consumption!
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Customer Reviews (3)
Write a reviewI greatly appreciate their commitment to ensuring my research is a success.
The YWHAZ Protein offers a wide range of applications, making it highly versatile for various experimental settings.
With the YWHAZ Protein, I have the confidence to generate critical insights and drive significant advancements in my field.
Q&As (5)
Ask a questionYWHAZ is involved in cardiovascular diseases by influencing processes like vascular smooth muscle cell proliferation and apoptosis.
Yes, elevated levels of YWHAZ protein have been detected in certain cancers, making it a potential biomarker for cancer diagnosis.
Preliminary studies suggest that YWHAZ levels may be altered in cardiovascular diseases, making it a candidate biomarker for further investigation.
Research suggests that targeting YWHAZ protein may be a viable strategy for developing anticancer therapies.
Investigational studies are exploring the modulation of YWHAZ as a potential therapeutic approach for neurodegenerative disorders.
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