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Recombinant Human YWHAZ Protein, Myc/DDK-tagged, C13 and N15-labeled

Cat.No. : YWHAZ-843H
Product Overview : YWHAZ MS Standard C13 and N15-labeled recombinant protein (NP_003397) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
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Description : This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene.
Source : HEK293
Species : Human
Tag : Myc&DDK
Molecular Mass : 27.6 kDa
AA Sequence : MDKNELVQKAKLAEQAERYDDMAAC MKSVTEQGAELSNEERNLLSVAYKN VVGARRSSWRVVSSIEQKTEGAEKK QQMAREYREKIETELRDICNDVLSL LEKFLIPNASQAESKVFYLKMKGDY YRYLAEVAAGDDKKGIVDQSQQAYQ EAFEISKKEMQPTHPIRLGLALNFS VFYYEILNSPEKACSLAKTAFDEAI AELDTLSEESYKDSTLIMQLLRDNL TLWTSDTQGDEAEAGEGGENTRTRP LEQKLISEEDLAANDILDYKDDDDK V
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
Gene Name : YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta [ Homo sapiens (human) ]
Official Symbol : YWHAZ
Synonyms : YWHAZ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide; tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein, delta polypeptide, YWHAD; 14-3-3 protein zeta/delta; 14 3 3 delta; 14 3 3 zeta; KCIP 1; 14-3-3 zeta; 14-3-3 delta; phospholipase A2; protein kinase C inhibitor protein 1; protein kinase C inhibitor protein-1; 14-3-3 protein/cytosolic phospholipase A2; tyrosine 3/tryptophan 5 -monooxygenase activation protein, zeta polypeptide; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, delta polypeptide; YWHAD; KCIP-1; 14-3-3-zeta; MGC111427; MGC126532; MGC138156;
Gene ID : 7534
mRNA Refseq : NM_003406
Protein Refseq : NP_003397
MIM : 601288
UniProt ID : P63104

Not For Human Consumption!

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Customer Reviews (3)

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10/17/2022

    I greatly appreciate their commitment to ensuring my research is a success.

    01/01/2022

      The YWHAZ Protein offers a wide range of applications, making it highly versatile for various experimental settings.

      11/16/2020

        With the YWHAZ Protein, I have the confidence to generate critical insights and drive significant advancements in my field.

        Q&As (5)

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        How does YWHAZ contribute to cardiovascular diseases? 09/03/2021

        YWHAZ is involved in cardiovascular diseases by influencing processes like vascular smooth muscle cell proliferation and apoptosis.

        Are there diagnostic applications of YWHAZ in cancer detection? 04/11/2021

        Yes, elevated levels of YWHAZ protein have been detected in certain cancers, making it a potential biomarker for cancer diagnosis.

        Is YWHAZ a potential biomarker for cardiovascular diseases? 01/27/2018

        Preliminary studies suggest that YWHAZ levels may be altered in cardiovascular diseases, making it a candidate biomarker for further investigation.

        Can YWHAZ protein be targeted for cancer treatment? 03/27/2016

        Research suggests that targeting YWHAZ protein may be a viable strategy for developing anticancer therapies.

        Are there potential therapeutic interventions targeting YWHAZ in neurodegenerative disorders? 03/18/2016

        Investigational studies are exploring the modulation of YWHAZ as a potential therapeutic approach for neurodegenerative disorders.

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