| Description : |
The protein encoded by this gene catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. This gene complements an X-linked mouse temperature-sensitive defect in DNA synthesis, and thus may function in DNA repair. It is part of a gene cluster on chromosome Xp11.23. Alternatively spliced transcript variants that encode the same protein have been described. [provided by RefSeq, Jul 2008] |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
117.8 kDa |
| AA Sequence : |
MSSSPLSKKRRVSGPDPKPGSNCSP AQSVLSEVPSVPTNGMAKNGSEADI DEGLYSRQLYVLGHEAMKRLQTSSV LVSGLRGLGVEIAKNIILGGVKAVT LHDQGTAQWADLSSQFYLREEDIGK NRAEVSQPRLAELNSYVPVTAYTGP LVEDFLSGFQVVVLTNTPLEDQLRV GEFCHNRGIKLVVADTRGLFGQLFC DFGEEMILTDSNGEQPLSAMVSMVT KDNPGVVTCLDEARHGFESGDFVSF SEVQGMVELNGNQPMEIKVLGPYTF SICDTSNFSDYIRGGIVSQVKVPKK ISFKSLVASLAEPDFVVTDFAKFSR PAQLHIGFQALHQFCAQHGRPPRPR NEEDAAELVALAQAVNARALPAVQQ NNLDEDLIRKLAYVAAGDLAPINAF IGGLAAQEVMKACSGKFMPIMQWLY FDALECLPEDKEVLTEDKCLQRQNR YDGQVAVFGSDLQEKLGKQKYFLVG AGAIGCELLKNFAMIGLGCGEGGEI IVTDMDTIEKSNLNRQFLFRPWDVT KLKSDTAAAAVRQMNPHIRVTSHQN RVGPDTERIYDDDFFQNLDGVANAL DNVDARMYMDRRCVYYRKPLLESGT LGTKGNVQVVIPFLTESYSSSQDPP EKSIPICTLKNFPNAIEHTLQWARD EFEGLFKQPAENVNQYLTDPKFVER TLRLAGTQPLEVLEAVQRSLVLQRP QTWADCVTWACHHWHTQYSNNIRQL LHNFPPDQLTSSGAPFWSGPKRCPH PLTFDVNNPLHLDYVMAAANLFAQT YGLTGSQDRAAVATFLQSVQVPEFT PKSGVKIHVSDQELQSANASVDDSR LEELKATLPSPDKLPGFKMYPIDFE KDDDSNFHMDFIVAASNLRAENYDI PSADRHKSKLIAGKIIPAIATTTAA VVGLVCLELYKVVQGHRQLDSYKNG FLNLALPFFGFSEPLAAPRHQYYNQ EWTLWDRFEVQGLQPNGEEMTLKQF LDYFKTEHKLEITMLSQGVSMLYSF FMPAAKLKERLDQPMTEIVSRVSKR KLGRHVRALVLELCCNDESGEDVEV PYVRYTIRTRTRPLEQKLISEEDLA ANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
