Recombinant Human UBR1 Protein, GST-tagged
Cat.No. : | UBR1-08H |
Product Overview : | Human UBR1 partial ORF ( NP_777576, 2 a.a. - 100 a.a.) recombinant protein with GST-tag at N-terminal was expressed in Wheat Germ. |
- Specification
- Gene Information
- Related Products
Description : | The N-end rule pathway is one proteolytic pathway of the ubiquitin system. The recognition component of this pathway, encoded by this gene, binds to a destabilizing N-terminal residue of a substrate protein and participates in the formation of a substrate-linked multiubiquitin chain. This leads to the eventual degradation of the substrate protein. The protein described in this record has a RING-type zinc finger and a UBR-type zinc finger. Mutations in this gene have been associated with Johanson-Blizzard syndrome. |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 36.63 kDa |
AA Sequence : | ADEEAGGTERMEISAELPQTPQRLA SWWDQQVDFYTAFLHHLAQLVPEIY FAEMDPDLEKQEESVQMSIFTPLEW YLFGEDPDICLEKLKHSGAFQLCG |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | UBR1 ubiquitin protein ligase E3 component n-recognin 1 [ Homo sapiens (human) ] |
Official Symbol : | UBR1 |
Synonyms : | UBR1; ubiquitin protein ligase E3 component n-recognin 1; JBS; E3 ubiquitin-protein ligase UBR1; E3a ligase; N-recognin-1; RING-type E3 ubiquitin transferase UBR1; ubiquitin ligase E3 alpha-I; ubiquitin-protein ligase E3-alpha; ubiquitin-protein ligase E3-alpha-1; ubiquitin-protein ligase E3-alpha-I; EC 2.3.2.27 |
Gene ID : | 197131 |
mRNA Refseq : | NM_174916 |
Protein Refseq : | NP_777576 |
MIM : | 605981 |
UniProt ID : | Q8IWV7 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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