- Cynomolgus Monkey(2)
- Homo sapiens (Human)(1)
- Human(7)
- Mouse(2)
- Mus musculus (Mouse)(1)
Recombinant Human UGT1A9 Protein
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Cat.No. : | UGT1A9-100H Optional Service: Optional requirements on this protein |
Product Overview : | Recombinant human UGT1A9 protein without tag was expressed in insect cells. |
Description : | This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene is active on phenols. |
Source : | Insect cells |
Species : | Human |
Bio-activity : | UGT Activity Data(Unless otherwise stated, all assays are carried out at 37 centigrade in 100 mM Tris-HCl (pH 7.5) containing 5 mM magnesium chloride and 2 mM UDPGA. Alamethicin (10 μg/ml final concentration) is added to kinetics tests only) Substrate: 17β-estradiol (3-glucuronide formation) Linear with time up to: 12 min(Determined at 4 μM substrate, using a protein concentration of 25 μg/ml) Linear with protein up to: 20 μg/ml(Determined at 4 μM substrate, using an incubation time of 5 min) Vmax: 10832 pmol/min/mg protein Km: 2.3 μM |
Usage : | For laboratory (research) purposes only |
Storage : | Store at -80 centigrade. Avoid frequent temperature changes. Thaw on ice. |
Concentration : | Protein Concentration: 5 mg/ml |
Storage Buffer : | 25 mM Tris-acetate (pH 7.6), 10% (v/v) glycerol, 1 mM EDTA |
Gene Name : | UGT1A9 UDP glucuronosyltransferase family 1 member A9 [ Homo sapiens (human) ] |
Official Symbol : | UGT1A9 |
Synonyms : | UGT1A9; UDP glucuronosyltransferase family 1 member A9; LUGP4; UDPGT; UGT1I; HLUGP4; UGT-1I; UGT1-9; UGT1.9; UGT1AI; UGT1-09; UGT1A9S; UDPGT 1-9; UDP-glucuronosyltransferase 1-9; UDP glucuronosyltransferase 1 family, polypeptide A9; UDP glycosyltransferase 1 family, polypeptide A9; UDP-glucuronosyltransferase 1 family polypeptide A9s; UDP-glucuronosyltransferase 1-I; UDP-glucuronosyltransferase 1A9 |
Gene ID : | 54600 |
mRNA Refseq : | NM_021027 |
Protein Refseq : | NP_066307 |
MIM : | 606434 |
UniProt ID : | O60656 |
◆ Recombinant Protein
UGT1A9-821C | Recombinant Cynomolgus Monkey UGT1A9 Protein, His (Fc)-Avi-tagged | +Inquiry |
UGT1A9-9890M | Recombinant Mouse UGT1A9 Protein, His (Fc)-Avi-tagged | +Inquiry |
UGT1A9-179H | Recombinant Human UGT1A9 Protein, GST/His-tagged | +Inquiry |
UGT1A9-1078C | Recombinant Cynomolgus UGT1A9 Protein, His-tagged | +Inquiry |
UGT1A9-3587H | Recombinant Human UGT1A9, GST-tagged | +Inquiry |
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◆ Lysates
UGT1A9-510HCL | Recombinant Human UGT1A9 293 Cell Lysate | +Inquiry |
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UGT2B10UGT1A1UGT1A10UGT1A3UGT1A6UGT1A9UGT2B4UGT1A7UGT2B15UGT2B17UGT2B7UGT3A1UGT3A2UGT1A4UGT1A5UGT2A3UGT2B11Ugt8aUgt1a2Ugt1a6aUgt1a7cUGT1A8UGT2A1Ugt2b5UGT8Ugt1a6bUgt2a2Ugt2b1UGT2B28Ugt2b34Ugt2b35Ugt2b36Ugt2b37Ugt2b38Ugt2b
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