Recombinant Human USP14
Cat.No. : | USP14-692H |
Product Overview : | Recombinant Human USP14 isproduced inE. coli. |
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Species : | Human |
Source : | E.coli |
Tag : | Non |
Description : | This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. Mice with a mutation that results in reduced expression of the ortholog of this protein are retarded for growth, develop severe tremors by 2 to 3 weeks of age followed by hindlimb paralysis and death by 6 to 10 weeks of age. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |
Storage : | -80°C. |
Gene Name | USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) [ Homo sapiens ] |
Synonyms | USP14; ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase); deubiquitinating enzyme 14; tRNA-guanine transglycosylase, 60-kD subunit; ubiquitin carboxyl-terminal hydrolase 14; ubiquitin specific protease 14 (tRNA-guanine transglycosylase); ubiquitin thioesterase 14; ubiquitin thiolesterase 14; ubiquitin-specific processing protease 14; ubiquitin-specific-processing protease 14; TGT; EC 3.1.2.15 |
Gene ID | 9097 |
mRNA Refseq | NM_001037334 |
Protein Refseq | NP_001032411 |
MIM | 607274 |
UniProt ID | P54578 |
Chromosome Location | 18p11.32 |
Function | cysteine-type endopeptidase activity; peptidase activity; proteasome binding; proteasome inhibitor activity; tRNA guanylyltransferase activity; ubiquitin thiolesterase activity; ubiquitin-specific protease activity |
◆ Native Proteins | ||
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LDH-15H | Native Human Lactate Dehydrogenase | +Inquiry |
TF-323H | Native Human Transferrin Fluorescein | +Inquiry |
C4A-2H | Native Human Complement C4 | +Inquiry |
◆ Cell & Tissue Lysates | ||
USP22-464HCL | Recombinant Human USP22 293 Cell Lysate | +Inquiry |
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FBXL6-601HCL | Recombinant Human FBXL6 cell lysate | +Inquiry |
SIRPA-2298HCL | Recombinant Human SIRPA cell lysate | +Inquiry |
Not For Human Consumption!
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