Recombinant Human VCL Protein, MYC/DDK-tagged

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Recombinant Human VCL Protein, MYC/DDK-tagged

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Cat.No. : VCL-118H
Product Overview : Recombinant human VCL protein, fused to MYC/DDK-tag at C-terminal, was expressed in HEK293.
Description : Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008].
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
Molecular Mass : 116.5 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : vinculin [ Homo sapiens ]
Official Symbol : VCL
Synonyms : CMD1W; CMH15; HEL114; MV; MVCL
Gene ID : 7414
mRNA Refseq : NM_003373.3
Protein Refseq : NP_003364.1
MIM : 193065
UniProt ID : P18206

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