Recombinant Monkey CD86 Protein, Fc-tagged, Alexa Fluor 647 conjugated
Cat.No. : | CD86-138CAF647 |
Product Overview : | Alexa Fluor 647 conjugated recombinant Monkey CD86 (Q9BDM4) (Met1-His239), fused with the Fc region of human IgG1 at the C-terminus, was produced in Human Cells. |
Availability | October 24, 2024 |
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Source : | HEK293 |
Species : | Monkey |
Tag : | Fc |
Form : | Lyophilized |
Molecular Mass : | The recombinant cynomolgus CD86 is a disulfide-linked homodimer. The reduced monomer comprises 461 amino acids and has a calculated molecular mass of 52.2 kDa.The apparent molecular mass of the protein is approximately 76-86 and 34 kDa respectively in SDS |
Protein length : | 461 |
N-terminal Sequence Analysis : | Leu 20 |
Endotoxin : | < 1.0 EU/ μg of the protein as determined by the LAL method. |
Purity : | (87.0+5.3) % as determined by SDS-PAGE |
Characteristic : | Disulfide-linked homodimer Labeled with Alexa Fluor 647 via amines Excitation = 650 nm Emission = 668 nm |
Stability : | Samples are stable for up to 12 months from date of receipt at -70 centigrade. |
Storage : | Store it under sterile conditions at -20 to -70 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Storage Buffer : | Lyophilized from sterile PBS, pH 7.4. Normally 5%-8% trehalose and mannitol are added as protectants before lyophilization. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution. Centrifuge the vial at 4 centigrade before opening to recover the entire contents. |
Gene Name : | CD86 centigrade D86 molecule [Macaca fascicularis(crab-eating macaque) ] |
Official Symbol : | CD86 |
Gene ID : | 102147235 |
mRNA Refseq : | XM_005547999 |
Protein Refseq : | XP_005548056 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (3)
Write a reviewWith the CD86 protein's high-quality composition and reliability, researchers can confidently proceed with their studies, knowing that they have access to a protein that consistently delivers accurate results.
Its high purity and stability ensure reliable and reproducible results, which are paramount for achieving meaningful scientific outcomes.
The CD86 protein is renowned for its outstanding quality, making it an optimal choice to fulfill the requirements of my experimental investigations.
Q&As (5)
Ask a questionYes, several clinical trials are investigating the efficacy of CD86 inhibitors in various diseases, including autoimmune disorders and certain cancers.
In transplantation, CD86 blockade is investigated as a potential strategy to modulate the immune response and prevent graft rejection by inhibiting excessive T cell activation.
CD86 signaling is involved in the differentiation of T helper cells. Modulating CD86 levels may influence the balance between Th1 and Th2 responses, which is relevant in various immune-mediated diseases.
There is emerging evidence suggesting that CD86 expression levels may have prognostic value in certain diseases, guiding clinicians in predicting disease outcomes.
CD86 signaling is involved in the development and function of regulatory T cells, which play a crucial role in maintaining immune tolerance and preventing autoimmune reactions.
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