Recombinant Mouse Alkbh8 Protein, Myc/DDK-tagged
Cat.No. : | Alkbh8-1603M |
Product Overview : | Purified recombinant protein of mouse full-length alkB homolog 8, tRNA methyltransferase (Alkbh8), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA via its methyltransferase domain. Catalyzes the last step in the formation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA. Has a preference for tRNA(Arg) and tRNA(Glu), and does not bind tRNA(Lys). Binds tRNA and catalyzes the iron and alpha-ketoglutarate dependent hydroxylation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA via its dioxygenase domain, giving rise to 5-(S)-methoxycarbonylhydroxymethyluridine; has a preference for tRNA(Gly). Required for normal survival after DNA damage. May inhibit apoptosis and promote cell survival and angiogenesis. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 74.8 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Alkbh8 alkB homolog 8, tRNA methyltransferase [ Mus musculus (house mouse) ] |
Official Symbol : | Alkbh8 |
Synonyms : | ALKBH8; alkB, alkylation repair homolog 8 (E. coli); alkylated DNA repair protein alkB homolog 8; probable alpha-ketoglutarate-dependent dioxygenase ABH8; tRNA (carboxymethyluridine(34)-5-O)-methyltransferase ABH8; S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8; Abh8; 4930562C03Rik; 8030431D03Rik; 9430088N01Rik; MGC10235 |
Gene ID : | 67667 |
mRNA Refseq : | NM_026303 |
Protein Refseq : | NP_080579 |
UniProt ID : | Q80Y20 |
Products Types
◆ Recombinant Protein | ||
ALKBH8-479M | Recombinant Mouse ALKBH8 Protein, His (Fc)-Avi-tagged | +Inquiry |
ALKBH8-322H | Recombinant Human ALKBH8 Protein, His (Fc)-Avi-tagged | +Inquiry |
ALKBH8-3274B | Recombinant Bovine ALKBH8, His-tagged | +Inquiry |
ALKBH8-1560M | Recombinant Mouse ALKBH8 Protein | +Inquiry |
ALKBH8-479H | Recombinant Human ALKBH8 Protein, GST-tagged | +Inquiry |
◆ Lysates | ||
ALKBH8-18HCL | Recombinant Human ALKBH8 lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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