Recombinant Mouse Amh Protein, MYC/DDK-tagged Amh-592M

Recombinant Mouse Amh Protein, MYC/DDK-tagged


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Recombinant Mouse Amh Protein, MYC/DDK-tagged

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Cat.No. : Amh-592M
Product Overview : Purified recombinant protein of full-length mouse anti-Mullerian hormone (Amh), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
Description : This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate N- and C-terminal cleavage products that homodimerize and associate to form a biologically active noncovalent complex. This complex binds to the anti-Mullerian hormone receptor type 2 and causes the regression of Mullerian ducts in the male embryo that would otherwise differentiate into the uterus and fallopian tubes. This protein also plays a role in Leydig cell differentiation and function and follicular development in adult females. Homozygous knockout male mice develop female reproductive organs and are often sterile, while homozygous knockout female mice exhibit premature depletion of primordial follicles.
Source : HEK293T
Species : Mouse
Molecular Mass : 59.8 kDa
Purity : >80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Amh anti-Mullerian hormone [ Mus musculus (house mouse) ]
Official Symbol : Amh
Synonyms : Amh; anti-Mullerian hormone; MIS; muellerian-inhibiting factor; Mullerian inhibiting substance; anti-Muellerian hormone; muellerian-inhibiting substance
Gene ID : 11705
mRNA Refseq : NM_007445
Protein Refseq : NP_031471
UniProt ID : Q5EC55

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