Recombinant Mouse Ang Protein, MYC/DDK-tagged


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Recombinant Mouse Ang Protein, MYC/DDK-tagged

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Cat.No. : Ang-602M
Product Overview : Purified recombinant protein of full-length mouse angiogenin, ribonuclease, RNase A family, 5 (Ang), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
Description : This gene encodes a member of the pancreatic ribonuclease A superfamily and is a potent inducer of neovascularization. The encoded protein is a secreted multifunctional tRNA-specific ribonuclease that promotes angiogenesis in response to angiogenetic stimuli such as hypoxia, mediates stress-induced translational repression by cleaving cellular tRNAs, stimulates cell proliferation by mediating rRNA transcription in prostate cancer cells, and is involved in neurite pathfinding. This gene resides in a cluster of highly related genes. It shares dual promoters and 5' exons with the ribonuclease, RNase A family 4 gene. Two alternatively spliced variants, with different 5' exons but the same coding exon, have been identified. Multiple pseudogenes have been found for this gene.
Source : HEK293T
Species : Mouse
Molecular Mass : 16.2 kDa
Purity : >80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Ang angiogenin, ribonuclease, RNase A family, 5 [ Mus musculus (house mouse) ]
Official Symbol : Ang
Synonyms : Ang; angiogenin, ribonuclease, RNase A family, 5; Ang1; Rnase5; Rnase5a; AI385586; angiogenin; RNase 5; angiogenin, ribonuclease A family, member 1; angiogenin-1; ribonuclease 5; EC 3.1.27.-
Gene ID : 11727
mRNA Refseq : NM_007447
Protein Refseq : NP_031473
UniProt ID : P21570
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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