Recombinant Mouse Apoa1 Protein, MYC/DDK-tagged

• Cat.No.: Apoa1-631M
• Product Overview: Purified recombinant protein of full-length mouse apolipoprotein A-I (Apoa1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: This gene encodes a preproprotein that is proteolytically cleaved to yield a signal peptide and a proproptein that is subsequently processed to generate the active mature peptide. The encoded protein is the major protein component of plasma high density lipoprotein (HDL). This protein facilitates the removal of cholesterol and other fats from tissues by transporting them to the liver for excretion. This protein is a cofactor for lecithin cholesterolacyltransferase, an enzyme that catalyzes the conversion of free cholesterol to cholesteryl esters. Mutations in this gene in humans causes familial HDL deficiency, Tangier disease and familial visceral amyloidosis. Similar clinical features are exhibited by mice with mutations in this gene. This gene is clustered with three other apolipoprotein genes on chromosome 9.
• Source: HEK293T
• Species: Mouse
• Tag: MYC/DDK
• Molecular Mass: 31.1 kDa
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Apoa1 apolipoprotein A-I [ Mus musculus (house mouse) ]
• Official Symbol: Apoa1
• Synonyms: Apoa1; apolipoprotein A-I; Sep2; Alp-1; Ltw-1; Sep-1; Sep-2; Apoa-1; Brp-14; Lvtw-1; apo-AI; apoA-I; apolipoprotein A-I; apolipoprotein A1
• Gene ID: 11806
• mRNA Refseq: NM_009692
• Protein Refseq: NP_033822
• UniProt ID: Q00623