Recombinant Mouse Arpc2 Protein, Myc/DDK-tagged

• Cat.No.: Arpc2-1725M
• Product Overview: Purified recombinant protein of mouse full-length actin related protein 2/3 complex, subunit 2 (Arpc2), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Actin-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the mother actin filament. In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA. The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs).
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 34.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Arpc2 actin related protein 2/3 complex, subunit 2 [ Mus musculus (house mouse) ]
• Official Symbol: Arpc2
• Synonyms: ARPC2; actin related protein 2/3 complex, subunit 2; actin-related protein 2/3 complex subunit 2; arp2/3 complex 34 kDa subunit; 34kDa; p34-Arc; 2210023N03Rik
• Gene ID: 76709
• mRNA Refseq: NM_029711
• Protein Refseq: NP_083987
• UniProt ID: Q9CVB6