Birc5-627M
Optional Service: Optional requirements on this protein
Product Overview :
Purified recombinant protein of full-length mouse baculoviral IAP repeat-containing 5 (Birc5), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
Description :
This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. In humans, gene expression is high during fetal development and in most tumors yet low in adult tissues. Antisense transcripts have been identified in human that regulate this gene's expression. At least three transcript variants encoding distinct isoforms have been found for this gene, although at least one of these transcript variants is a nonsense-mediated decay (NMD) candidate.
Source :
HEK293T
Species :
Mouse
Tag :
MYC/DDK
Molecular Mass :
14.2 kDa
Purity :
>80% as determined by SDS-PAGE and Coomassie blue staining
Stability :
Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage :
Store at -80 centigrade after receiving vials.
Concentration :
>50 μg/mL as determined by microplate BCA method
Storage Buffer :
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.