Recombinant Mouse Birc7 Protein, Myc/DDK-tagged
Cat.No. : | Birc7-1870M |
Product Overview : | Purified recombinant protein of mouse full-length baculoviral IAP repeat-containing 7 (livin) (Birc7), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
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- Gene Information
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Description : | Apoptotic regulator capable of exerting proapoptotic and anti-apoptotic activities and plays crucial roles in apoptosis, cell proliferation, and cell cycle control. Its anti-apoptotic activity is mediated through the inhibition of caspase-3, -7, and -9, as well as by its E3 ubiquitin-protein ligase activity. As it is a weak caspase inhibitor, its anti-apoptotic activity is thought to be due to its ability to ubiquitinate DIABLO/SMAC targeting it for degradation thereby promoting cell survival. May contribute to caspase inhibition, by blocking the ability of DIABLO/SMAC to disrupt XIAP/BIRC4-caspase interactions. Protects against apoptosis induced by TNF or by chemical agents such as adriamycin, etoposide or staurosporine. Suppression of apoptosis is mediated by activation of MAPK8/JNK1, and possibly also of MAPK9/JNK2. This activation depends on TAB1 and NR2C2/TAK1. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 32.4 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Birc7 baculoviral IAP repeat-containing 7 (livin) [ Mus musculus (house mouse) ] |
Official Symbol : | Birc7 |
Synonyms : | BIRC7; baculoviral IAP repeat-containing 7 (livin); baculoviral IAP repeat-containing protein 7; KIAP; Livin; ML-IAP; E130019N06 |
Gene ID : | 329581 |
mRNA Refseq : | NM_001163247 |
Protein Refseq : | NP_001156719 |
UniProt ID : | A2AWP0 |
Products Types
◆ Recombinant Protein | ||
BIRC7-0093H | Recombinant Human BIRC7 Protein (M1-S298), His tagged | +Inquiry |
BIRC7-1036M | Recombinant Mouse BIRC7 Protein, His (Fc)-Avi-tagged | +Inquiry |
BIRC7-0092H | Recombinant Human BIRC7 Protein (M1-S298), Tag Free | +Inquiry |
BIRC7-449H | Recombinant Human BIRC7 Protein, His (Fc)-Avi-tagged | +Inquiry |
BIRC7-229H | Active Recombinant Human BIRC7 protein(Met1-Ser298), His-tagged | +Inquiry |
◆ Lysates | ||
BIRC7-8448HCL | Recombinant Human BIRC7 293 Cell Lysate | +Inquiry |
BIRC7-8447HCL | Recombinant Human BIRC7 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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