Recombinant Mouse Cabp1 Protein, Myc/DDK-tagged

• Cat.No.: Cabp1-1922M
• Product Overview: Purified recombinant protein of mouse full-length calcium binding protein 1 (Cabp1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Modulates calcium-dependent activity of inositol 1,4,5-triphosphate receptors (ITPRs). Inhibits agonist-induced intracellular calcium signaling. Enhances inactivation and does not support calcium-dependent facilitation of voltage-dependent P/Q-type calcium channels. Causes calcium-dependent facilitation and inhibits inactivation of L-type calcium channels by binding to the same sites as calmodulin in the C-terminal domain of CACNA1C, but has an opposite effect on channel function. Suppresses the calcium-dependent inactivation of CACNA1D. Inhibits TRPC5 channels. Prevents NMDA receptor-induced cellular degeneration. Required for the normal transfer of light signals through the retina.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 25.9 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Cabp1 calcium binding protein 1 [ Mus musculus (house mouse) ]
• Official Symbol: Cabp1
• Synonyms: CABP1; calcium binding protein 1; calcium-binding protein 1
• Gene ID: 29867
• mRNA Refseq: NM_013879
• Protein Refseq: NP_038907
• UniProt ID: Q9JLK7