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Recombinant Mouse CAD Protein

Cat.No. : CAD-2634M
Product Overview : Recombinant Mouse CAD full length or partial length protein was expressed.
  • Specification
  • Gene Information
  • Related Products
Source : Mammalian Cells
Species : Mouse
Tag : His
Form : Liquid or lyophilized powder
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method.
Purity : >80%
Notes : This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
Storage : Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC.
Storage Buffer : PBS buffer
Gene Name : Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase [ Mus musculus ]
Official Symbol : CAD
Gene ID : 69719
mRNA Refseq : NM_023525.1
Protein Refseq : NP_076014.1
MIM :
UniProt ID : B2RQC6

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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What are the allosteric regulators of CAD, and how do they affect its activity? 08/07/2021

CAD is allosterically regulated by UTP, which inhibits its activity, and ATP, which activates it. These nucleotides bind to specific sites on CAD and modulate its function, helping to control pyrimidine biosynthesis.

What is the molecular function of CAD, and how does it play a central role in de novo pyrimidine biosynthesis? 03/22/2021

CAD is a multi-domain enzyme that catalyzes three sequential reactions in de novo pyrimidine biosynthesis: carbamoyl phosphate synthesis, aspartate carbamoylation, and dihydroorotate formation.

How does CAD contribute to maintaining nucleotide balance in the cell? 05/11/2020

CAD helps maintain nucleotide balance by ensuring an adequate supply of pyrimidine nucleotides. When the cell needs more pyrimidines, CAD activity increases, and when there is an excess, CAD is allosterically inhibited.

What are some general techniques used to study CAD at the molecular level? 06/01/2019

Researchers use techniques like X-ray crystallography, nuclear magnetic resonance (NMR) spectroscopy, and enzyme assays to study CAD's structure and function. These methods provide insights into its bio-molecular chemistry.

What is the allosteric regulation of CAD by UTP and ATP, and how do these nucleotides affect its activity? 10/04/2018

CAD is allosterically regulated by UTP and ATP. UTP negatively regulates CAD, while ATP positively regulates it. UTP binds to an allosteric site, promoting the formation of the less active CAD tetramer, whereas ATP stabilizes the more active CAD dimer.

Customer Reviews (3)

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Reviews
04/03/2021

    Product arrived quickly and as described.

    02/09/2020

      This product works wonders.

      09/23/2019

        Quick shipping and well-packaged.

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