Recombinant Mouse CAD Protein
Cat.No. : | CAD-2634M |
Product Overview : | Recombinant Mouse CAD full length or partial length protein was expressed. |
- Specification
- Gene Information
- Related Products
Source : | Mammalian Cells |
Species : | Mouse |
Tag : | His |
Form : | Liquid or lyophilized powder |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method. |
Purity : | >80% |
Notes : | This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications. |
Storage : | Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC. |
Storage Buffer : | PBS buffer |
Gene Name : | Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase [ Mus musculus ] |
Official Symbol : | CAD |
Gene ID : | 69719 |
mRNA Refseq : | NM_023525.1 |
Protein Refseq : | NP_076014.1 |
MIM : | |
UniProt ID : | B2RQC6 |
Products Types
◆ Recombinant Protein | ||
CAD-1179M | Recombinant Mouse CAD Protein, His (Fc)-Avi-tagged | +Inquiry |
CAD-10649H | Recombinant Human CAD, His-tagged | +Inquiry |
CAD-1966Z | Recombinant Zebrafish CAD | +Inquiry |
CAD-49H | Recombinant Human CAD protein, His-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionCAD is allosterically regulated by UTP, which inhibits its activity, and ATP, which activates it. These nucleotides bind to specific sites on CAD and modulate its function, helping to control pyrimidine biosynthesis.
CAD is a multi-domain enzyme that catalyzes three sequential reactions in de novo pyrimidine biosynthesis: carbamoyl phosphate synthesis, aspartate carbamoylation, and dihydroorotate formation.
CAD helps maintain nucleotide balance by ensuring an adequate supply of pyrimidine nucleotides. When the cell needs more pyrimidines, CAD activity increases, and when there is an excess, CAD is allosterically inhibited.
Researchers use techniques like X-ray crystallography, nuclear magnetic resonance (NMR) spectroscopy, and enzyme assays to study CAD's structure and function. These methods provide insights into its bio-molecular chemistry.
CAD is allosterically regulated by UTP and ATP. UTP negatively regulates CAD, while ATP positively regulates it. UTP binds to an allosteric site, promoting the formation of the less active CAD tetramer, whereas ATP stabilizes the more active CAD dimer.
Customer Reviews (3)
Write a reviewProduct arrived quickly and as described.
This product works wonders.
Quick shipping and well-packaged.
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