Recombinant Mouse Castor1 Protein, Myc/DDK-tagged
Cat.No. : | Castor1-1970M |
Product Overview : | Purified recombinant protein of mouse full-length cytosolic arginine sensor for mTORC1 subunit 1 (Castor1), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Functions as an intracellular arginine sensor within the amino acid-sensing branch of the TORC1 signaling pathway. As a homodimer or a heterodimer with CASTOR2, binds and inhibits the GATOR subcomplex GATOR2 and thereby mTORC1. Binding of arginine to CASTOR1 allosterically disrupts the interaction of CASTOR1-containing dimers with GATOR2 which can in turn activate mTORC1 and the TORC1 signaling pathway. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 36.6 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Castor1 cytosolic arginine sensor for mTORC1 subunit 1 [ Mus musculus (house mouse) ] |
Official Symbol : | Castor1 |
Synonyms : | Castor1; cytosolic arginine sensor for mTORC1 subunit 1; Gat; Gatsl3; 2410008K03Rik; cytosolic arginine sensor for mTORC1 subunit 1; GATS protein-like 3; GATS-like protein 3 |
Gene ID : | 71962 |
mRNA Refseq : | NM_028022 |
Protein Refseq : | NP_082298 |
UniProt ID : | Q9CWQ8 |
Products Types
◆ Recombinant Protein | ||
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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