Recombinant Mouse Cd163 protein, His-tagged

• Cat.No.: Cd163-1849M
• Product Overview: Recombinant Mouse Cd163 aa. (Pro697~Gly972) fused with N-terminal His tag was produced in E. coli cells.

Specification

• Source: E. coli
• Species: Mouse
• Tag: His
• Form: Freeze-dried powder
• Molecular Mass: 34kDa as determined by SDS-PAGE reducing conditions.
• Protein length: Pro697~Gly972
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 6.3.
• Applications: SDS-PAGE; WB; ELISA; IP; CoIP; Purification; Amine Reactive Labeling.
• Stability: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Concentration: 200ug/mL
• Storage buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5%Trehalose and Proclin300.
• Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: Cd163 CD163 antigen [ Mus musculus (house mouse) ]
• Official Symbol: Cd163
• Synonyms: Cd163; CD163 antigen; CD163v2; CD163v3; scavenger receptor cysteine-rich type 1 protein M130
• Gene ID: 93671
• mRNA Refseq: NM_053094.2
• Protein Refseq: NP_444324.2
• UniProt ID: Q2VLH6

Reviews

01/25/2023

The outstanding performance of CD163 protein in both ELISA and protein electron microscopy structure analysis positions it as a highly valuable asset in diverse research areas.

09/09/2019

Its ability to accurately detect proteins and visualize their structures offers a valuable toolkit for advancing scientific understanding and discoveries.

01/13/2016

Whether it is protein-protein interactions, enzymatic assays, or cellular studies, CD163 protein delivers consistent and accurate data, making it a valuable tool for researchers.

Q&As

How does CD163 contribute to the understanding of cardiovascular diseases?

CD163 is implicated in the development and progression of cardiovascular diseases, serving as a marker for inflammation in atherosclerosis.

In what ways does CD163 contribute to the understanding of cancer progression?

CD163 expression is studied in the context of cancer to evaluate its role in promoting or inhibiting tumor growth and metastasis.

How is CD163 involved in the pathogenesis of neurodegenerative diseases?

CD163 is being investigated for its potential role in neurodegenerative diseases, where neuroinflammation is a key factor.

Are there diagnostic assays or imaging techniques that utilize CD163 as a molecular target?

Some diagnostic assays and imaging techniques use CD163 as a molecular target to visualize and quantify inflammatory processes in vivo.

How is CD163 linked to autoimmune disorders such as lupus?

CD163 expression is associated with the pathogenesis of autoimmune disorders, and its modulation is being explored for therapeutic purposes.