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Recombinant Mouse Cd33 protein, Fc-tagged, R-PE labeled

Cat.No. : Cd33-6889MP
Product Overview : Recombinant Mouse Cd33 protein, Fc-tagged was Conjugated with NH2-Reactive R-PE(R-Phycoerythrin).
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Description : NH2-Reactive R-Phycoerythrin is used for antibody conjugation for immunostaining and cellular proteins for tracing. NH2-Reactive R-Phycoerythrin has succinimidyl ester groups, and can easily make a covalent bond with amino groups of protein without any activation process.
Source : HEK293
Species : Mouse
Tag : Fc
Form : Liquid in sterile PBS buffer pH 7.4 (may contains tiny amount of reaction buffer and R-Phycoerythrin).
Endotoxin : <1EU/ug by LAL method.
Stability : Sample is stable for at least 12 months when stored at -20 to -80°C from date of manufacture. For longer storage, add equal volume of glycerol to the sample solution and store at -20 to -80°C.
Storage : Store under sterile conditions at -20 to -80°C immediately after receipt. It is recommended that the protein be aliquoted for optimal storage. Avoid freeze-thaw cycles.
Related Product : Cd33-6889M
Official Symbol : Cd33
Synonyms : CD33; CD33 antigen; myeloid cell surface antigen CD33; sialic acid-binding Ig-like lectin 3; gp67; Siglec-3;
Official Symbol : Cd33
Synonyms : CD33; CD33 antigen; myeloid cell surface antigen CD33; sialic acid-binding Ig-like lectin 3; gp67; Siglec-3;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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What are the implications of CD33 polymorphisms in therapeutic targeting? 10/18/2022

Certain polymorphisms in the CD33 gene can influence its expression on the cell surface, which might affect the efficacy of CD33-targeted therapies.

What is the primary biological function of CD33 in hematopoietic cells? 10/08/2022

CD33 is a transmembrane receptor primarily expressed on cells of myeloid lineage and is involved in modulating cellular functions, including the regulation of cellular proliferation and differentiation.

How does CD33 expression vary among different leukocyte populations? 01/11/2022

CD33 is predominantly expressed on myeloid cells, especially on immature myeloid cells. Its expression decreases as these cells differentiate and is typically low or absent on lymphoid cells.

How has CD33 been utilized as a therapeutic target in hematological malignancies? 09/22/2021

CD33 has been targeted for therapeutic antibodies in AML. An example is gemtuzumab ozogamicin, which targets CD33 and delivers a cytotoxic agent specifically to leukemia cells expressing CD33.

How does CD33 signaling influence myeloid cell differentiation? 06/08/2020

While the exact signaling pathways of CD33 are still under investigation, it is believed that CD33 signaling can influence the differentiation and function of myeloid cells, potentially playing a role in immune regulation.

What role does CD33 play in acute myeloid leukemia (AML)? 03/30/2019

CD33 is commonly expressed on the surface of AML blasts, making it a potential target for therapeutic interventions in AML.

Are there known ligands that bind specifically to CD33? 06/20/2018

The specific ligands for CD33 are not fully characterized, but it is believed to play a role in cell-cell interactions within the immune system.

Customer Reviews (3)

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Reviews
11/14/2019

    Quick dissolution, easy use.

    08/27/2019

      Excellent solubility, no aggregates.

      02/27/2019

        High concentration, very effective.

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