Cat.No.:	Cd40-81M
Product Overview:	Recombinant mouse CD40, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Description:	CD40, also known as tumor necrosis factor receptor superfamily member, is receptor for TNFSF5/CD40LG. It transduces TRAF6 and MAP3K8 mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion.
Source:	Insect cell
Species:	Mouse
Tag:	His
Form:	Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.
Molecular Mass:	20.1kDa (180aa)18-28KDa (SDS–PAGE under reducing conditions.)
AA Sequence:	LGQCVTCSDK QYLHDGQCCD LCQPGSRLTS HCTALEKTQC HPCDSGEFSA QWNREIRCHQ HRHCEPNQGL RVKKEGTAES DTVCTCKEGQ HCTSKDCEAC AQHTPCIPGF GVMEMATETT DTVCHPCPVG FFSNQSSLFE KCYPWTSCED KNLEVLQKGT SQTNVICGLK SRMRHHHHHH
Endotoxin:	< 1.0 EU per 1 microgram of protein (determined by LAL method)
Purity:	: >95% by SDS – PAGE
Storage:	Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
Concentration:	1.0mg/ml (determined by Absorbance at 280nm)

Gene Name:	Cd40 CD40 antigen [ Mus musculus ]
Official Symbol:	Cd40
Synonyms:	CD40; CD40 antigen; tumor necrosis factor receptor superfamily member 5; CD40L receptor; B-cell surface antigen CD40; T-cell differentiation antigen; tumor necrosis factor receptor superfamily, member 5; IGM; p50; Bp50; GP39; IMD3; TRAP; HIGM1; T-BAM; Tnfrsf5; AI326936;
Gene ID:	21939
mRNA Refseq:	NM_011611
Protein Refseq:	NP_035741
MIM:
UniProt ID:
Pathway:	Adaptive Immune System, organism-specific biosystem; Allograft rejection, organism-specific biosystem; Allograft rejection, conserved biosystem; Asthma, organism-specific biosystem; Asthma, conserved biosystem; Autoimmune thyroid disease, organism-specific biosystem; Autoimmune thyroid disease, conserved biosystem;
Function:	binding; enzyme binding; protein binding; receptor activity;

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