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Recombinant Mouse Cdc42 Protein, MYC/DDK-tagged

Cat.No. : Cdc42-856M
Product Overview : Purified recombinant protein of full-length mouse cell division cycle 42 (Cdc42), with C-terminal MYC/DDK tag, was expressed in HEK293T cells.
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Description : Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Plays a role in the extension and maintenance of the formation of thin, actin-rich surface projections called filopodia. Mediates CDC42-dependent cell migration.
Source : HEK293T
Species : Mouse
Tag : MYC/DDK
Molecular Mass : 21.7 kDa
Purity : >80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 µg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Cdc42 cell division cycle 42 [ Mus musculus (house mouse) ]
Official Symbol : Cdc42
Synonyms : Cdc42; cell division cycle 42; AI747189; AU018915; cell division control protein 42 homolog; G25K GTP-binding protein
cell division cycle 42 homolog; EC 3.6.5.2
Gene ID : 12540
mRNA Refseq : NM_009861
Protein Refseq : NP_033991
UniProt ID : P60766

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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How does CDC42 regulate cytoskeletal reorganization and cell morphology changes? 02/11/2022

CDC42 controls cytoskeletal dynamics, leading to changes in cell shape and movement.

What is the impact of CDC42 on neuronal development and synaptic plasticity? 06/13/2019

CDC42 is important in neuronal development and plays a role in forming and remodeling synaptic connections.

How do alterations in CDC42 expression or activity affect aging and age-related diseases? 12/08/2018

Changes in CDC42 activity can impact aging processes and contribute to the development of age-related diseases.

How does CDC42 contribute to cancer cell migration, invasion, and metastasis? 10/30/2018

CDC42 facilitates cancer progression by enhancing cell migration, invasion, and metastatic potential.

How does CDC42 influence wound healing and tissue regeneration? 08/06/2018

CDC42 aids in wound healing and regeneration by guiding cell migration and tissue restructuring.

What role does CDC42 play in the process of cell division and cell cycle regulation? 07/14/2018

CDC42 is crucial for cell division and cycle progression, coordinating cellular events for proper division.

What are the mechanisms by which CDC42 modulates immune cell trafficking and activation? 07/02/2018

CDC42 regulates immune cell movement and activation, essential for immune response and surveillance.

Customer Reviews (3)

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Reviews
03/28/2021

    Reliable protein crystallography, essential for structural studies.

    09/08/2019

      Exceptional protein engineering services, meets our lab's needs.

      05/01/2018

        Efficient peptide synthesis, crucial for our peptide research.

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