Recombinant Mouse Cmtm4 Protein, Myc/DDK-tagged
Cat.No. : | Cmtm4-2211M |
Product Overview : | Purified recombinant protein of mouse full-length CKLF-like MARVEL transmembrane domain containing 4 (Cmtm4), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Acts as a backup for CMTM6 to regulate plasma membrane expression of PD-L1/CD274, an immune inhibitory ligand critical for immune tolerance to self and antitumor immunity. May protect PD-L1/CD274 from being polyubiquitinated and targeted for degradation. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 22.9 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Cmtm4 CKLF-like MARVEL transmembrane domain containing 4 [ Mus musculus (house mouse) ] |
Official Symbol : | Cmtm4 |
Synonyms : | CMTM4; CKLF-like MARVEL transmembrane domain containing 4; CKLF-like MARVEL transmembrane domain-containing protein 4; chemokine-like factor super family 4; chemokine-like factor superfamily member 4; D19397; Gm9853; Cklfsf4; MGC30490; MGC32180; ENSMUSG00000051554 |
Gene ID : | 97487 |
mRNA Refseq : | NM_153582 |
Protein Refseq : | NP_705810 |
UniProt ID : | Q8CJ61 |
Products Types
◆ Recombinant Protein | ||
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CMTM4-36H | Recombinant Human CMTM4 protein, MYC/DDK-tagged | +Inquiry |
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CMTM4-35H | Recombinant Human CMTM4 protein, GST-tagged | +Inquiry |
CMTM4-3635M | Recombinant Mouse CMTM4 Protein | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionAltered expression of CMTM4 protein has been associated with disease progression in certain cancers, indicating its potential as a prognostic marker for these diseases.
CMTM4 protein has been shown to enhance T cell activation and effector functions, suggesting its role in modulating immune responses against cancer and infections.
Researchers are exploring the possibility of targeting CMTM4 protein to modulate immune responses and potentially develop new therapeutic interventions for cancer and autoimmune diseases.
Dysregulation of CMTM4 protein expression has been linked to autoimmune diseases, highlighting its potential as a target for developing new treatments for these conditions.
CMTM4 protein interacts with and modulates the activity of immune checkpoint molecules, influencing the function of immune cells and their responses to tumors and pathogens.
Customer Reviews (3)
Write a reviewThe CMTM4 protein comes highly recommended for a variety of applications, particularly in ELISA and protein electron microscopy structure analysis.
Researchers can rely on the CMTM4 protein's specificity and sensitivity to obtain accurate and reliable results.
researchers highly recommend the CMTM4 protein due to its excellent performance in ELISA and its suitability for protein electron microscopy structure analysis.
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