Recombinant Mouse Cnot4 Protein, Myc/DDK-tagged

• Cat.No.: Cnot4-2221M
• Product Overview: Purified recombinant protein of mouse full-length CCR4-NOT transcription complex, subunit 4 (Cnot4), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Has E3 ubiquitin ligase activity, promoting ubiquitination and degradation of target proteins. Involved in activation of the JAK/STAT pathway. Catalyzes ubiquitination of methylated RBM15.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 77.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Cnot4 CCR4-NOT transcription complex, subunit 4 [ Mus musculus (house mouse) ]
• Official Symbol: Cnot4
• Synonyms: CNOT4; CCR4-NOT transcription complex, subunit 4; CCR4-NOT transcription complex subunit 4; CCR4-associated factor 4; transcriptional repressor NOT4Hp; E3 ubiquitin-protein ligase CNOT4; negative regulator of transcription 4; potential transcriptional repressor NOT4Hp; Not4; Not4h; Not4hp
• Gene ID: 53621
• mRNA Refseq: NM_001164413
• Protein Refseq: NP_001157885
• UniProt ID: Q8BT14