Recombinant Mouse Cnot7 Protein, Myc/DDK-tagged
Cat.No. : | Cnot7-2223M |
Product Overview : | Purified recombinant protein of mouse full-length CCR4-NOT transcription complex, subunit 7 (Cnot7), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Its function seems to be partially redundant with that of CNOT8. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. During miRNA-mediated repression the complex seems also to act as translational repressor during translational initiation. Additional complex functions may be a consequence of its influence on mRNA expression. Required for miRNA-mediated mRNA deadenylation. Associates with members of the BTG family such as TOB1 and BTG2 and is required for their anti-proliferative activity. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 32.7 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Cnot7 CCR4-NOT transcription complex, subunit 7 [ Mus musculus (house mouse) ] |
Official Symbol : | Cnot7 |
Synonyms : | CNOT7; CCR4-NOT transcription complex, subunit 7; CCR4-NOT transcription complex subunit 7; CAF-1; POP2 homolog; CCR4-associated factor 1; catabolite repressor protein (CCR4)-associative factor 1; Caf1; Pop2; AU022737 |
Gene ID : | 18983 |
mRNA Refseq : | NM_011135 |
Protein Refseq : | NP_035265 |
UniProt ID : | Q60809 |
Products Types
◆ Recombinant Protein | ||
CNOT7-631H | Recombinant Human CNOT7 Protein, His (Fc)-Avi-tagged | +Inquiry |
CNOT7-1587H | Recombinant Human CNOT7 Protein, GST-tagged | +Inquiry |
CNOT7-766R | Recombinant Rhesus Macaque CNOT7 Protein, His (Fc)-Avi-tagged | +Inquiry |
CNOT7-39H | Recombinant Human CNOT7 protein | +Inquiry |
Cnot7-3640R | Recombinant Mouse Cnot7, His-tagged | +Inquiry |
◆ Lysates | ||
CNOT7-7399HCL | Recombinant Human CNOT7 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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