Recombinant Mouse Cntfr Protein, MYC/DDK-tagged CNTFR-3683M

Recombinant Mouse Cntfr Protein, MYC/DDK-tagged


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Recombinant Mouse Cntfr Protein, MYC/DDK-tagged

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Cat.No. : Cntfr-3683M
Product Overview : Purified recombinant protein of Mouse ciliary neurotrophic factor receptor (Cntfr), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
Description : This gene encodes the alpha subunit of the ciliary neurotrophic factor (CNTF) receptor that triggers the assembly of a trimolecular complex upon binding to CNTF, and initiate a downstream signaling process. The encoded preproprotein undergoes proteolytic processing to generate a glycosylphosphatidylinositol-linked cell surface protein. Mice lacking the encoded protein die shortly after birth and exhibit a reduction of motoneuron number at birth. The transgenic disruption of this gene specifically in the skeletal muscle followed by a peripheral nerve lesion impairs motor neuron axonal regeneration across the lesion site. Alternative splicing of this gene results in multiple transcript variants.
Source : HEK293T
Species : Mouse
Molecular Mass : 40.8 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Cntfr ciliary neurotrophic factor receptor [ Mus musculus (house mouse) ]
Official Symbol : Cntfr
Synonyms : Cntfr; ciliary neurotrophic factor receptor; Cntfralpha; ciliary neurotrophic factor receptor subunit alpha; CNTF receptor subunit alpha
Gene ID : 12804
mRNA Refseq : NM_016673
Protein Refseq : NP_057882
UniProt ID : O88507

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