Recombinant Mouse Cyp2e1 Protein, Myc/DDK-tagged
Cat.No. : | Cyp2e1-2417M |
Product Overview : | Purified recombinant protein of mouse full-length cytochrome P450, family 2, subfamily e, polypeptide 1 (Cyp2e1), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 57.3 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 [ Mus musculus (house mouse) ] |
Official Symbol : | Cyp2e1 |
Synonyms : | CYP2E1; cytochrome P450, family 2, subfamily e, polypeptide 1; cytochrome P450 2E1; CYPIIE1; cytochrome P450-J; cytochrome P450-ALC; 4-nitrophenol 2-hydroxylase; cytochrome P450, 2e1, ethanol inducible; Cyp2e |
Gene ID : | 13106 |
mRNA Refseq : | NM_021282 |
Protein Refseq : | NP_067257 |
UniProt ID : | Q05421 |
Products Types
◆ Recombinant Protein | ||
CYP2E1-890H | Recombinant Human CYP2E1 Protein, His-tagged | +Inquiry |
CYP2E1-79H | Active Recombinant Human CYP2E1 Protein | +Inquiry |
CYP2E1-1373M | Recombinant Mouse CYP2E1 Protein (2-493 aa), His-tagged | +Inquiry |
CYP2E1-1397R | Recombinant Rat CYP2E1 Protein, His (Fc)-Avi-tagged | +Inquiry |
CYP2E1-0005H | Recombinant Human CYP2E1 Protein (L32-S493), Tag Free | +Inquiry |
◆ Lysates | ||
CYP2E1-7111HCL | Recombinant Human CYP2E1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionGenetic polymorphisms in CYP2E1 can result in altered enzyme activity, influencing an individual's response to drugs and susceptibility to liver damage.
CYP2E1 oxidizes and metabolizes various small molecules, including drugs and toxins.
It plays a significant role in ethanol metabolism and helps detoxify industrial solvents and other xenobiotics.
Ethanol, fasting, and certain drugs can induce the expression of CYP2E1.
CYP2E1 activity generates ROS, contributing to oxidative stress and potential cellular damage.
CYP2E1 is highly expressed in the liver, which is the main site for drug metabolism.
CYP2E1 can contribute to drug-drug interactions, affecting the efficacy and toxicity of co-administered drugs.
Customer Reviews (3)
Write a reviewProduct is as described.
Fast and efficient service.
Great for biological experiments.
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