Active Recombinant Mouse FAP protein, His-Avi-tagged, Biotinylated
Cat.No. : | FAP-321MB |
Product Overview : | Biotinylated Recombinant Mouse FAP protein(Leu 26 - Asp 761), fused with His and Avi tag, was expressed in HEK293. |
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Source : | HEK293 |
Species : | Mouse |
Tag : | His-Avi |
Form : | Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization. |
Bio-activity : | Immobilized Biotinylated Mouse FAP, His,Avitag at 1 μg/mL (100 μL/well) on streptavidin precoated (0.5 μg/well) plate can bind Anti-FAP Antibody, Mouse IgG2a (FAP5) with a linear range of 0.2-6 ng/mL.Immobilized Anti-FAP Antibody, Mouse IgG2a (FAP5) at 5 μg/mL (100 μL/well) can bind Biotinylated Mouse FAP, His,Avitag with a linear range of 1-20 ng/mL.Measured by its ability to convert the substrate benzyloxycarbonyl-Gly-Pro-7-amido-4-methylcoumarin (Z-GP-AMC) to Z-Gly-Pro and 7-amino-4-methylcoumarin (AMC). The specific activity is >3500 pmol/min/µg. |
Molecular Mass : | This protein carries a polyhistidine tag at the N-terminus, followed by an Avi tag (Avitag™).The protein has a calculated MW of 92.7 kDa. The protein migrates as 80-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Protein Length : | Leu26-Asp761 |
Endotoxin : | Less than 1.0 EU per μg by the LAL method. |
Purity : | >95% as determined by SDS-PAGE.>90% as determined by SEC-MALS. |
Storage : | For long term, the product should be stored at lyophilized state at -20°C or lower.Please protect from light and avoid repeated freeze-thaw cycles.This product is stable after at: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | Fap fibroblast activation protein [ Mus musculus ] |
Official Symbol : | FAP |
Synonyms : | FAP; fibroblast activation protein; seprase; integral membrane serine protease; fibroblast activation protein alpha; |
Gene ID : | 14089 |
mRNA Refseq : | NM_007986 |
Protein Refseq : | NP_032012 |
Products Types
◆ Recombinant Protein | ||
Fap-1018M | Recombinant Mouse Fap Protein, MYC/DDK-tagged | +Inquiry |
FAP-006H | Active Recombinant Human FAP Protein, His-tagged | +Inquiry |
Fap-10552M | Recombinant Mouse Fap Protein, His (Fc)-Avi-tagged | +Inquiry |
Fap-01M | Active Recombinant Mouse Fap Protein | +Inquiry |
FAP-03H | Active Recombinant Human FAP Protein (Leu26-Asp760), N-6×His tagged | +Inquiry |
◆ Lysates | ||
FAP-1881HCL | Recombinant Human FAP cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-1729 | FAP Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionFAP can suppress the immune response by modulating the activity of certain immune cells, creating an immunosuppressive tumor microenvironment.
High levels of FAP expression in tumors have been associated with poor prognosis, making it a potential prognostic marker for certain cancers.
Yes, several clinical trials are investigating the safety and efficacy of FAP-targeted therapies in various cancer types.
FAP-targeted therapies are being explored for conditions such as fibrotic diseases and rheumatoid arthritis, extending its potential clinical applications.
Molecular imaging techniques, such as positron emission tomography (PET), can be employed to visualize FAP expression in tumors noninvasively.
Customer Reviews (3)
Write a reviewIt enables accurate detection and quantification of FAP protein levels in samples, providing crucial insights into its expression, regulation, and potential functional changes under different experimental conditions.
FAP protein is highly recommended for researchers due to its excellent performance in various assays, particularly in Western blotting (WB) experiments, and its applicability in protein electron microscopy structure analysis.
FAP protein is highly recommended for researchers, as it demonstrates excellent performance in WB experiments and has proven useful in protein electron microscopy structure analysis.
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