Active Recombinant Mouse Gdf5 Protein
Cat.No. : | Gdf5-065M |
Product Overview : | Purified recombinant protein of Mouse growth differentiation factor 5 (Gdf5) without tag was expressed in E.coli. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates the development of numerous tissue and cell types, including cartilage, joints, brown fat, teeth, and the growth of neuronal axons and dendrites. Mice with a mutation in this gene exhibit enhanced tooth enamel formation. |
Source : | E. coli |
Species : | Mouse |
Bio-activity : | Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 1.0-2.0 ug/ml. |
Molecular Mass : | 27 kDa |
AA Sequence : | APLANRQGKRPSKNLKARCSRKALH VNFKDMGWDDWIIAPLEYEAFHCEG LCEFPLRSHLEPTNHAVIQTLMNSM DPESTPPTCCVPTRLSPISILFIDS ANNVVYKQYEDMVVESCGCR |
Endotoxin : | Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg) |
Purity : | >95%, as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for at least 6 months from date of receipt under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. |
Storage Buffer : | Lyophilized from a 0.2 µM filtered solution of 20mM phosphate buffer,100mM NaCl, pH 7.2 |
Reconstitution : | Resuspend the protein in the desired concentration in proper buffer. |
Gene Name : | Gdf5 growth differentiation factor 5 [ Mus musculus (house mouse) ] |
Official Symbol : | Gdf5 |
Synonyms : | Gdf5; growth differentiation factor 5; bp; brp; BMP-14; Cdmp-1; growth/differentiation factor 5; bone morphogenetic protein 14; cartilage-derived morphogenetic protein-1 |
Gene ID : | 14563 |
mRNA Refseq : | NM_008109 |
Protein Refseq : | NP_032135 |
UniProt ID : | P43027 |
Products Types
◆ Recombinant Protein | ||
GDF5-049H | Active Recombinant Human GDF5 Protein | +Inquiry |
GDF5-107H | Active Recombinant Human GDF5 Protein | +Inquiry |
Gdf5-276M | Recombinant Mouse Gdf5 Protein, His-tagged | +Inquiry |
GDF5-275H | Recombinant Human GDF5 Protein, His-tagged | +Inquiry |
GDF5-299H | Active Recombinant Human GDF5 Protein (Ala382-Arg501), C-His tagged, Animal-free, Carrier-free | +Inquiry |
◆ Lysates | ||
GDF5-5968HCL | Recombinant Human GDF5 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket